ID B6H788_PENRW Unreviewed; 582 AA.
AC B6H788;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Pc16g02170 protein {ECO:0000313|EMBL:CAP92887.1};
GN ORFNames=Pc16g02170 {ECO:0000313|EMBL:CAP92887.1}, PCH_Pc16g02170
GN {ECO:0000313|EMBL:CAP92887.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP92887.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP92887.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- FUNCTION: Probable lipid hydrolase. {ECO:0000256|ARBA:ARBA00002682}.
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DR EMBL; AM920431; CAP92887.1; -; Genomic_DNA.
DR RefSeq; XP_002560589.1; XM_002560543.1.
DR AlphaFoldDB; B6H788; -.
DR STRING; 500485.B6H788; -.
DR GeneID; 8313949; -.
DR KEGG; pcs:Pc16g02170; -.
DR VEuPathDB; FungiDB:PCH_Pc16g02170; -.
DR eggNOG; KOG2214; Eukaryota.
DR HOGENOM; CLU_009031_5_0_1; -.
DR OMA; SIVPWPH; -.
DR OrthoDB; 154387at2759; -.
DR BioCyc; PCHR:PC16G02170-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006641; P:triglyceride metabolic process; IEA:UniProt.
DR CDD; cd07229; Pat_TGL3_like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR021771; Triacylglycerol_lipase_N.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF44; TRIACYLGLYCEROL LIPASE 3; 1.
DR Pfam; PF11815; DUF3336; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT DOMAIN 185..378
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REGION 546..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 561..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 65846 MW; 37A9E1C07F5E5D56 CRC64;
MGSWWLGLWN IVGAVWNMVL DVAQFWRDKL LSWWHSKSPR DRLFHTLANA QSYEEWEEAA
FELDELQSKD IWRQNPVSRH YDYRLILGRL EALMGARESE DILTLVNLLR SGLVRNLGNI
TSTKLFTHAY AGTKLLIDDY ITQVALSIQY VTSVPGAPMH PSGFSSQAKL ELLHDTRQAF
GRTTLLLQGG SAFGLCHLGV VKALHLQGLL PRIITGTATG AMIAALVGIH SEDELLPLLD
GEGLDLSAFE RRKMVSGGGE GNSDYSWVGT FYRRMKRLLR KGYLFDVGVL EECVRANVGD
LTFEEAYARS KRILNITVAT TEKNGTPNLL NYLTAPNVLI WSAAVASNAS SSGLYSPVTI
YCKDETGTII PWPHTQDTVF RPWRHVQYNE GESPLSRISE LFNVNHFIVS QARPYLVPFL
RSELNLLDRR QTGWNNLSRS AMRLMIVELR HRLRQLDYLG VLPAPLSRLL IDETIPGPNL
TLVPDLCFWD LRKLFQSPTK ERVSEWTLKG ERGVWPAISA LKVREAVEIE LDRGYQLVRR
RRPSDASLSV SVPKQVNAMN EGVPRRRRGE SENEEGILAD RE
//
