ID B6HAT2_PENRW Unreviewed; 354 AA.
AC B6HAT2;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Pc16g13920 protein {ECO:0000313|EMBL:CAP94062.1};
GN ORFNames=Pc16g13920 {ECO:0000313|EMBL:CAP94062.1}, PCH_Pc16g13920
GN {ECO:0000313|EMBL:CAP94062.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP94062.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP94062.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; AM920431; CAP94062.1; -; Genomic_DNA.
DR RefSeq; XP_002561690.1; XM_002561644.1.
DR AlphaFoldDB; B6HAT2; -.
DR STRING; 500485.B6HAT2; -.
DR GeneID; 8311468; -.
DR KEGG; pcs:Pc16g13920; -.
DR VEuPathDB; FungiDB:PCH_Pc16g13920; -.
DR eggNOG; KOG1198; Eukaryota.
DR HOGENOM; CLU_026673_16_1_1; -.
DR OMA; MAICYEA; -.
DR OrthoDB; 2267374at2759; -.
DR BioCyc; PCHR:PC16G13920-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c16.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR CDD; cd08249; enoyl_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR45348:SF6; TRANS-ENOYL REDUCTASE APDC; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT DOMAIN 11..350
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 354 AA; 37642 MW; 2C7CFC30476D8A0D CRC64;
MHTQRAIIAE GPSRVRIDSD VEIPQPGDNE VLVKVHSVAL NPVDWKTLAY SSTPGAVSGC
DFSGTIAGPA GPKSQRVWNA GDRVCGWVMG GNPLRPSNGS FAEYVVAKAD LLFKIPDGTS
FETAATLGIS ASTGGLALFK TLGLSFAERK VTPSSPAVLV YGAATSSGII AIQLLQHAGY
RAIAVCSPQN FGLVNDLGAE VAFDYHSVTC GKDIRAYTHD DLGHALDCIS STSSMAICYD
ALRSQPGARY VSLDPFPDRV QRSRPEILAD WILTFSLTGD EVGFAGVFHR DPTPADYSFG
VSWYPKVDRM LEEGKLRPHQ PTIMGGGLAG VADGLEKLKK GEVHASKLVY NVGE
//
