ID B6HCB7_PENRW Unreviewed; 658 AA.
AC B6HCB7;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Pc18g05710 protein {ECO:0000313|EMBL:CAP94795.1};
GN ORFNames=Pc18g05710 {ECO:0000313|EMBL:CAP94795.1}, PCH_Pc18g05710
GN {ECO:0000313|EMBL:CAP94795.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP94795.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP94795.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; AM920433; CAP94795.1; -; Genomic_DNA.
DR RefSeq; XP_002562398.1; XM_002562352.1.
DR AlphaFoldDB; B6HCB7; -.
DR STRING; 500485.B6HCB7; -.
DR GeneID; 8306703; -.
DR KEGG; pcs:Pc18g05710a; -.
DR VEuPathDB; FungiDB:PCH_Pc18g05710; -.
DR eggNOG; KOG1179; Eukaryota.
DR HOGENOM; CLU_000022_46_3_1; -.
DR OMA; VWRQFLD; -.
DR OrthoDB; 1650656at2759; -.
DR BioCyc; PCHR:PC18G05710-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c18.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43107:SF15; FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A; 1.
DR PANTHER; PTHR43107; LONG-CHAIN FATTY ACID TRANSPORT PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 125..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..447
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 658 AA; 73218 MW; 322E7705E30BE40C CRC64;
MANKRSLCAE IPLSLALPAA ATTLAYLNAR WSLSYDLNLL KGLLKMSAKS RIAERGDRLN
LFYTLEAYAL DPKTADNDFI VYNGRTTTFH ETYITALRYG AWFKTVHGIK RKEIVAIDFM
NSSTFIFMLL GLWSIGAVPA FINYNLSGKP LTHSIRTSSA RLVVVDEEVR HCFPEEQEKI
LTSPNFRDGK GPVEIVFHTP EVEAQILGME PMREDDKARS GLIPRDMAIL IYTSGTTGLP
KPAIVSWKKC WSGSLFVKDW LNITPSDRFF TCMPLYHSSA AILGFITCLM GGSTLIIGRR
FSARNFMKEA RENGATVIQY VGETLRYLLG VAPEIDPVTG DDLDKKHNIR LAFGNGLRPD
IWNRFKERFN IPTIAEFYAA TEGTAGSWNI SSNDFSAGAI GRNGALGNII LGRGSAIVDV
DHETQEPWRD PKTGLCKKVP RGDPGELLFA IDAADPTANF QGYFGNKKAT EGKIIRDVIK
KGDAYFRTGD MVRWDKDGRW FFSDRLGDTF RWKSENVSTS EVSEVLGAHP EVHEANVYGV
SLPNHDGRAG CAAILFNQQI TSGGLSDSAL EPSREVLDTL AAHTLQNLPR FAAPLFLRVT
PVTQSTGNNK QQKHVLRTEG VDPALVSKKD RLYWLQGNTY VPFGQRDWER LTGGQVRL
//
