ID   B6HDM9_PENRW            Unreviewed;       960 AA.
AC   B6HDM9;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Pc20g12430 protein {ECO:0000313|EMBL:CAP86572.1};
GN   ORFNames=Pc20g12430 {ECO:0000313|EMBL:CAP86572.1}, PCH_Pc20g12430
GN   {ECO:0000313|EMBL:CAP86572.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP86572.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP86572.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- SIMILARITY: Belongs to the XPO2/CSE1 family.
CC       {ECO:0000256|ARBA:ARBA00008669}.
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DR   EMBL; AM920435; CAP86572.1; -; Genomic_DNA.
DR   RefSeq; XP_002563728.1; XM_002563682.1.
DR   AlphaFoldDB; B6HDM9; -.
DR   STRING; 500485.B6HDM9; -.
DR   GeneID; 8308486; -.
DR   KEGG; pcs:Pc20g12430; -.
DR   VEuPathDB; FungiDB:PCH_Pc20g12430; -.
DR   eggNOG; KOG1992; Eukaryota.
DR   HOGENOM; CLU_009614_0_0_1; -.
DR   OMA; AENEFLM; -.
DR   OrthoDB; 178772at2759; -.
DR   BioCyc; PCHR:PC20G12430-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c20.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR005043; XPO2_C.
DR   InterPro; IPR013713; XPO2_central.
DR   PANTHER; PTHR10997:SF8; EXPORTIN-2; 1.
DR   PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1.
DR   Pfam; PF03378; CAS_CSE1; 1.
DR   Pfam; PF08506; Cse1; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724}.
FT   DOMAIN          21..94
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   960 AA;  108363 MW;  314F2A191A3573FC CRC64;
     MAEGLGALLE ASLDPRQNKA AEITLRQEEQ KPGFSLQLLH ITASETTPYN TRLASALCFK
     NFIKRNWTDE DGNYKLQLDE VTTLKRELIS LMISVPPGIQ SQLGEAVSVI ADSDFWERWD
     TLVDDLVSKL SPGNPTVNIG VLQVAHSIFK RWRPLFQSDA LYTEINHVLG KFGTPFLALF
     EALDNYLEQN KANKENLTQG FTQLNLMVKL FYDLSSHDLP PMFEDNISGI ATIFLKYLTY
     DNQLLHTDEE TEAGLLEYVR AGIFEALTLY VQKYMDVFQP HVGQFIGSSW SFLTTIGQET
     KYDILVSRAL HFLTSVAGMP EHAAAFQAEE TLGQIVEKVI LPNVSLRESD EELFEDEPIE
     FIRRDLEGSD SETRRRAATD FLRKLAEKFE EPVTQVVLKY TQHYLGEYAK DSSNWKAKDT
     ATYLYSAIAA KGTATASHGV TATNQLVSIT DYFQQNLAAD LINEGGVHPI LKVDAIKYLY
     TFRSIITKEQ WLQVLPVLVK HLASSNFVVY TYAAIALERV LFLTDSQGQA VIPPTEITPL
     AKDLLEHIFQ LIQSNPAPEK VQENEFLMRC VMRVLVVIKE GVVPFTDLVL QRFINITNII
     SANPSNPRFY YFHFEAMGAF IRFAAPANPD KLEQALYAPF AAILQNDVQE FMPYVFQLFA
     ALLEANPSGT LPAYYQELIG PILMPVMWDS KGNIPALVRL LSSIIPRGSQ FIIEHKQIEP
     ILGIFQKLVS TKANESFGFD LLETVVANFP PTALENYFVM IMQIILQRLQ NSKTENLTMR
     FIRFFHFISA QDNKGYSADF VIQVTDKVQE GLFTPIYVNV ILPETQKLAR PLDRKTAIVS
     FTKTLANSEA FATRYSQKGW GFTCTALLKL LELPPLPASR DDLINDADIE DMSFGVGFTP
     LNTIRAQQKD PWPETGADLK AWVGSYLKEA DKKQNGRISQ FAQERLDDQS KTVLASYISQ
//