ID B6JUV7_SCHJY Unreviewed; 754 AA.
AC B6JUV7;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Rho-type GTPase activating protein Rga6 {ECO:0000313|EMBL:EEB05036.1};
GN Name=rga6 {ECO:0000313|JaponicusDB:SJAG_00028};
GN ORFNames=SJAG_00028 {ECO:0000313|EMBL:EEB05036.1};
OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB05036.1, ECO:0000313|Proteomes:UP000001744};
RN [1] {ECO:0000313|EMBL:EEB05036.1, ECO:0000313|Proteomes:UP000001744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE651166; EEB05036.1; -; Genomic_DNA.
DR RefSeq; XP_002171329.1; XM_002171293.2.
DR AlphaFoldDB; B6JUV7; -.
DR STRING; 402676.B6JUV7; -.
DR EnsemblFungi; EEB05036; EEB05036; SJAG_00028.
DR GeneID; 7049255; -.
DR JaponicusDB; SJAG_00028; rga6.
DR VEuPathDB; FungiDB:SJAG_00028; -.
DR eggNOG; ENOG502SAYM; Eukaryota.
DR HOGENOM; CLU_369249_0_0_1; -.
DR OrthoDB; 2729610at2759; -.
DR Proteomes; UP000001744; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IEA:UniProt.
DR GO; GO:0032153; C:cell division site; IEA:UniProt.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0008360; P:regulation of cell shape; IMP:JaponicusDB.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR PANTHER; PTHR15228:SF25; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001744}.
FT DOMAIN 283..511
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 82..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..134
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 754 AA; 82954 MW; A67EED7D329C6D51 CRC64;
MSVNTSTPAF NAGTQFYLAH TSSLSSLQVS EKWQQSPNTN NCISHANTSV MAHSFLETFH
TLAEAHRIPT VTINDMVPHC PATPTPDGRP YTSGGLIPFV SSSGNDEIDG SPNVRRTKRY
SIRSSPKRSR SQLLHRHSVF VPSSPSSFQP MHSATLSSDR ISSLNESADS ANGNNLLGFA
SSESSLALRP KTSAYGSSVH TSQDSPDTAD LKRAHRNSWT FFLRHPSTSH LQRKFSISGN
SPSSTHHSRN LSSRTNLLAS SRSVFGKDIL ALPDNESTFC EPDALPSHAL PASLRVPHVF
SQCITALISH GLAVPGIFRI SGSGPVIRAI MDYYFEPPSF WYEDPEDLFQ KIGEPTAIDI
AGVLKRYILM LPGGLLGRQE VLDLLVSLHH APNQQELPKN VWLEMTVLAL AQIDSYRRFS
VFASLFALLH LIVLKTQQVE QSLADIGEST YMRAEALGIV FGPLLLGMSD EPYSTKIDGA
QLNDVMRFET EKVRLEAKIV ENIINNWPGL VAEMRRLEVA AAFPDSPENV TKEENVTVTR
NPSTIVEVPS SRALVSQRNS ALFNSNVPAD LFFTPMSTAF SFYPENDTRN QVSFSFADDS
SLTNMQPEDP SVRQTSPLSP SLLEETTRAV LESNNDAGVT VSSSSNEKDL ENQLTPAHVS
EAEAIQSFIK STSTLPLPTK NIRRAETVIL SAPTSKATED NVLSDRKLKA RTVTAIPSDG
TTSSKSDKKE SKHGFSRFYK RINIFRRLFK KKKT
//
