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Database: UniProt
Entry: B6JVU9_SCHJY
LinkDB: B6JVU9_SCHJY
Original site: B6JVU9_SCHJY 
ID   B6JVU9_SCHJY            Unreviewed;       834 AA.
AC   B6JVU9;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 2.
DT   07-JUN-2017, entry version 36.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=SJAG_00516 {ECO:0000313|EMBL:EEB05500.2};
OS   Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales;
OC   Schizosaccharomycetaceae; Schizosaccharomyces.
OX   NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB05500.2, ECO:0000313|Proteomes:UP000001744};
RN   [1] {ECO:0000313|EMBL:EEB05500.2, ECO:0000313|Proteomes:UP000001744}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K.,
RA   Guo Y., Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K.,
RA   Bayne E.H., Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L.,
RA   FitzGerald M.G., French C., Gujja S., Hansen K., Keifenheim D.,
RA   Levin J.Z., Mosher R.A., Mueller C.A., Pfiffner J., Priest M.,
RA   Russ C., Smialowska A., Swoboda P., Sykes S.M., Vaughn M.,
RA   Vengrova S., Yoder R., Zeng Q., Allshire R., Baulcombe D.,
RA   Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J., Levin H.,
RA   Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; KE651166; EEB05500.2; -; Genomic_DNA.
DR   RefSeq; XP_002171793.2; XM_002171757.2.
DR   STRING; 402676.XP_002171793.1; -.
DR   EnsemblFungi; EEB05500; EEB05500; SJAG_00516.
DR   GeneID; 7048014; -.
DR   EuPathDB; FungiDB:SJAG_00516; -.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   OrthoDB; EOG092C0YCY; -.
DR   Proteomes; UP000001744; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:EnsemblFungi.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001744};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001744};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    432    456       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    476    495       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    552    571       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    583    607       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    650    672       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    775    795       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   834 AA;  93461 MW;  AE7DC96A9F190D27 CRC64;
     MAPSLYRSEN VSLVQLFLPT ESARATVAAL GRLSTIQFRD LNPDVTPFQR SFVKEIRRLN
     ETQRQLRYFH AEITSAGIPI KEGPSENTEL INSSTVEEVM DQCNTLDSRI RQLADSSKSL
     NERYERLLQL RNVLIKTNAF FNQSNEGLVL SSLDESALHA SHEDDDELAA PLMGSSAVEL
     DTTTTPTTLS ESGHPSIPID FVAGVIPTAK FQYLERILWR TLRGNLYIYH VPADLPTGSN
     DDGLADAQTI FLVFAHGTQI LSKIRKISDS LGSTLFTVED NAARRLDQLR DVNDRIGDLS
     SVLDNMKNAL FTELSFVADH LSHWETLLHT DKCVYQAMNL FIFDQNHKCL IAEGWCPQDN
     LPLVQASLRD VSQRLGSQAP TILNVLETSE VPPTYHRTNK FTEGFQSIID SYGIASYREV
     NHGIVAIVTF PFLFAIMFGD LGHGAIMFAI ALAFILNEKK LGAKKDLDEM VGMVFFGRYI
     LLLMGAFSMY TGFLYNDIFS KPLSLFTSGW HWPSKASGDL LRAVEVGTYP IGVDPAWHSA
     DNNLLFMNSY KMKLSVIFGI VHMTFCLFLS LSNYRFFKKK LDIYAVFIPS LIFLESIFGY
     LVVTIIYKWS VDWNGLGLRA PGLLNMLILM FLSPGTIAEP LYPGQKYVQL ILLGAALICV
     PWLLCAKPIA LYRQHKKATA PKYLSLRDSD DTAEDANLLS SVTEADPKDH EDFELGEIVI
     HQVIHTIEFC LGCISHTASY LRLWALSLAH NQLSTVLWNM TIANGFRMTG VSGSIAIFIL
     FAFWFVITCA VLVAMEGTSA MLHSLRLHWV EGMSKHFEGE GYAFTPFNFI ENAE
//
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