ID B6K158_SCHJY Unreviewed; 603 AA.
AC B6K158;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Membrane transporter {ECO:0000313|EMBL:EEB07679.1};
GN ORFNames=SJAG_02780 {ECO:0000313|EMBL:EEB07679.1};
OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB07679.1, ECO:0000313|Proteomes:UP000001744};
RN [1] {ECO:0000313|EMBL:EEB07679.1, ECO:0000313|Proteomes:UP000001744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Allantoate
CC permease family. {ECO:0000256|ARBA:ARBA00037968}.
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DR EMBL; KE651166; EEB07679.1; -; Genomic_DNA.
DR RefSeq; XP_002173972.1; XM_002173936.2.
DR AlphaFoldDB; B6K158; -.
DR STRING; 402676.B6K158; -.
DR EnsemblFungi; EEB07679; EEB07679; SJAG_02780.
DR GeneID; 7049443; -.
DR JaponicusDB; SJAG_02780; -.
DR VEuPathDB; FungiDB:SJAG_02780; -.
DR eggNOG; KOG2533; Eukaryota.
DR HOGENOM; CLU_001265_0_0_1; -.
DR OMA; WTANSKE; -.
DR OrthoDB; 1749674at2759; -.
DR Proteomes; UP000001744; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015225; F:biotin transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1901604; F:dethiobiotin transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015295; F:solute:proton symporter activity; IBA:GO_Central.
DR GO; GO:1905135; P:biotin import across plasma membrane; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43791:SF96; MEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR43791; PERMEASE-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001744};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 140..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 559..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 29..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 66599 MW; CBC1F8C327C3E0F1 CRC64;
MHLHPSAASP MQLPTQPANV VTVDRTVTTT DESPSGSVTL HKGTASADSS GSLGSISSMK
TVQTNDSYKS EKLNDLVTFD ETLRDIDPKG VSPVNTNDET VIPSDESFYE EGEKEIPWTA
EETQALSVIR RKCDFRIISC IWLTYFLSRS VTYSVSMSYT MNTSDGHSLL QTVKGINSHT
LSIGLAVSYV ALIVFDLPSN LLMTCADPRL WLSRIQLSTG IIGACHTILG SRISRPSTFI
ILRLFNGLAI AGMWPGFAYY TSRWYRDRHL GKRIGWYYTA AQIASVTTSL LSAVFQKMDN
LGGLYGFQWM FLIWGIVTFL QGLTIGPWLP PIKCGNKGEK LFSWIPCPRF LNFLRPAKES
HLTPKEKQLH KRYMRGLNVG RSWNWRDLVA ATLDARLWPP IFMFFGVVGV SNGIANYSSL
IVRQIDASFS DVTVSLLVAP IYIFNTLAIL TVLPLHDRYK RKALFFVSSA CIILAGLLVT
TFTPGVWGRY IGLLILGFGL GPTVPIIMAW VSDAMGPTHG DVGVAAGLAI VSGLGNIGSV
ISTYALYSGW KSDTTYRKSN EVMCGMVGIA IVAAIAMHCI QKFHWYSPTR TRLCVRKTDE
EKA
//
