ID B6QF66_TALMQ Unreviewed; 682 AA.
AC B6QF66;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=20S cyclosome subunit (APC8), putative {ECO:0000313|EMBL:EEA24101.1};
GN ORFNames=PMAA_081140 {ECO:0000313|EMBL:EEA24101.1};
OS Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS (Penicillium marneffei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA24101.1, ECO:0000313|Proteomes:UP000001294};
RN [1] {ECO:0000313|Proteomes:UP000001294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC {ECO:0000313|Proteomes:UP000001294};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS995901; EEA24101.1; -; Genomic_DNA.
DR RefSeq; XP_002147612.1; XM_002147576.1.
DR AlphaFoldDB; B6QF66; -.
DR STRING; 441960.B6QF66; -.
DR VEuPathDB; FungiDB:PMAA_081140; -.
DR HOGENOM; CLU_018320_2_0_1; -.
DR OrthoDB; 3131281at2759; -.
DR PhylomeDB; B6QF66; -.
DR Proteomes; UP000001294; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR007192; APC8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR Pfam; PF04049; ANAPC8; 1.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 12..327
FT /note="Cdc23"
FT /evidence="ECO:0000259|Pfam:PF04049"
FT REPEAT 388..421
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 422..455
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 45..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 118..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..594
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 77186 MW; 03502E2AD6C21E4C CRC64;
MAMTFTENSI KELRLRLEDA VLKCSERCLY QSAKWAAEML NSLVPTDGND TDAESPMETD
PQPNVNPFSG QSDPTEAALE LQEAHKYLLA KSYFDTREYD RCAAVFLPPT IPPVPLSNVS
PNVKTRASLT PQKGKRKSFI RPGSKAGQAL PRNPYPNLSQ KSLFLALYAK YLAGEKRRDE
ETEMVLGPAD GGMTVNRELP DLARGLEGWF ADRQERGLQD RGQGWLEYLY AVILIKGKNE
EEAKKWLVRS VHLFPFHWGA WQELNDLLPS VDDLKQVAET LPQNIMSFIF QVHCSQELYQ
ATDETHQTLN GLESIFPTSA FLKTERALLY YHSRDFEDAS AIFADILIES PHRLDSLDHY
SNILYVMGAR PQLAFVAQLA TATDKFRPET CCVVGNYYSL KSEHEKAVMY FRRALTLDRN
FLSAWTLMGH EYIEMKNTHA AIESYRRAVD VNRKDYRAWY GLGQAYEVLD MCFYALYYYQ
RTAALKPYDP KMWQAVGTCY AKMGQLPQSI KAMKRALVAG AYYEQGPNAA TADHPAAGRK
VLDPDLLHQI ALLYERLGDE DEAAAYMELT LQQESGEIER TETDSDDDGD DANSDDETTT
RSQRQRRRQK SRGDDDEVEA VGGTGVTATT SKARLWLARW SLKHGELNRA DQLAGELCQD
GIEVEEAKAL MRDVRARREG GG
//
