ID B6RP68_9HIV1 Unreviewed; 209 AA.
AC B6RP68;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:ACA24342.1};
DE Flags: Fragment;
GN Name=pol {ECO:0000313|EMBL:ACA24342.1};
OS Human immunodeficiency virus 1.
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX NCBI_TaxID=11676 {ECO:0000313|EMBL:ACA24342.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:ACA24342.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BR06SP696 {ECO:0000313|EMBL:ACA24342.1};
RA Oliveira C.M., Almeida F.J., Rodrigues R., Crozatti M., Vazquez C.M.P.,
RA Ferrao M.S.C., Campeas A.E., Marques S.R., Brigido L.F.M.;
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACA24342.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BR06SP696 {ECO:0000313|EMBL:ACA24342.1};
RX PubMed=18716710; DOI=10.1007/s00705-008-0178-7;
RA de Oliveira C.M., Almeida F.J., Rodrigues R., Crozatti M., Vazquez C.M.,
RA do Socorro Carneiro Ferrao M., Campeas A.E., Marques S.R., Berezin E.N.,
RA de Macedo Brigido L.F.;
RT "High frequency of BF mosaic genomes among HIV-1-infected children from Sao
RT Paulo, Brazil.";
RL Arch. Virol. 153:1799-1806(2008).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EU258030; ACA24342.1; -; Genomic_DNA.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR41694; ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN; 1.
DR PANTHER; PTHR41694:SF3; RNA-DIRECTED DNA POLYMERASE-RELATED; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918,
KW ECO:0000313|EMBL:ACA24342.1}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral release from host cell {ECO:0000256|ARBA:ARBA00023113};
KW Virion maturation {ECO:0000256|ARBA:ARBA00023113}.
FT DOMAIN 25..209
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACA24342.1"
FT NON_TER 209
FT /evidence="ECO:0000313|EMBL:ACA24342.1"
SQ SEQUENCE 209 AA; 24438 MW; AEF8BFD741E732B2 CRC64;
RVKQWPLTEE KIKALVEICT EMEKEGKISK IGPENPYNTP VFAIKKKDST KWRKLVDFRE
LNKRTQDFWE VQLGIPHPAG LKKKKSVTVL DVGDAYFSVP LDPDFRKYTA FTIPSTNNET
PGIRYQYNVL PQGWKGSPAI FQSSMTKILE PFRKQNPEIV IYQYMDDLYV GSDLEIGQHR
TKIEELRQHL LRWGFTTPDK KHQKEPPFL
//
