ID B6V6Y5_AERME Unreviewed; 283 AA.
AC B6V6Y5;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:ACJ06173.1};
OS Aeromonas media.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=651 {ECO:0000313|EMBL:ACJ06173.1};
RN [1] {ECO:0000313|EMBL:ACJ06173.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ER.1.18 {ECO:0000313|EMBL:ACJ06178.1}, ER.1.19
RC {ECO:0000313|EMBL:ACJ06179.1}, and ER.1.8
RC {ECO:0000313|EMBL:ACJ06173.1};
RX PubMed=22127350; DOI=10.1016/j.resmic.2011.10.010;
RA Moura A., Pereira C., Henriques I., Correia A.;
RT "Novel gene cassettes and integrons in antibiotic-resistant bacteria
RT isolated from urban wastewaters.";
RL Res. Microbiol. 163:92-100(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; FJ238495; ACJ06173.1; -; Genomic_DNA.
DR EMBL; FJ238500; ACJ06178.1; -; Genomic_DNA.
DR EMBL; FJ238501; ACJ06179.1; -; Genomic_DNA.
DR AlphaFoldDB; B6V6Y5; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.670; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR001241; Topo_IIA.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013759; Topo_IIA_B_C.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SMART; SM00433; TOP2c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 81..250
FT /note="DNA topoisomerase type IIA subunit B"
FT /evidence="ECO:0000259|Pfam:PF00204"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACJ06173.1"
FT NON_TER 283
FT /evidence="ECO:0000313|EMBL:ACJ06173.1"
SQ SEQUENCE 283 AA; 31566 MW; 27A83D222E919B61 CRC64;
VYEQTYHLGE PQAPLKQIGD STGTGTEVRF WPSPTIFTDT LYHYEILAKR LRELSFLNSG
VSIRLMDERD GREAHFCYEG GIKAFVEYLN QNKTPIHPKV FHFTTEQDGI GVEVAMQWND
AYQEGVYCFT NNIPQRDGGT HLVGFRTALT RTLNSYMDKE DYSKKAKSAA SGDDVREGLI
AVISVKVPDP KFSSQTKDKL VSSEVKTAVE QAMGEKLADF LLENPGDAKI VVNKIIDAAR
AREAARKARE LTRRKGALDI AGLPGKLADC QEKDPALSEL YIV
//
