ID B6XTR5_9BIFI Unreviewed; 734 AA.
AC B6XTR5;
DT 20-JAN-2009, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2009, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=BIFCAT_00543 {ECO:0000313|EMBL:EEB21585.1};
OS Bifidobacterium catenulatum DSM 16992 = JCM 1194 = LMG 11043.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=566552 {ECO:0000313|EMBL:EEB21585.1, ECO:0000313|Proteomes:UP000003882};
RN [1] {ECO:0000313|EMBL:EEB21585.1, ECO:0000313|Proteomes:UP000003882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16992 {ECO:0000313|EMBL:EEB21585.1,
RC ECO:0000313|Proteomes:UP000003882};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Bifidobacterium catenulatum (DSM 16992).";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB21585.1, ECO:0000313|Proteomes:UP000003882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16992 {ECO:0000313|EMBL:EEB21585.1,
RC ECO:0000313|Proteomes:UP000003882};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEB21585.1}.
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DR EMBL; ABXY01000011; EEB21585.1; -; Genomic_DNA.
DR RefSeq; WP_003834445.1; NZ_JDTP01000027.1.
DR AlphaFoldDB; B6XTR5; -.
DR GeneID; 45583024; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG2815; Bacteria.
DR Proteomes; UP000003882; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06577; PASTA_pknB; 3.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.10.20; -; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR45832:SF24; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR Pfam; PF03793; PASTA; 3.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00740; PASTA; 4.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51178; PASTA; 2.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EEB21585.1};
KW Transferase {ECO:0000313|EMBL:EEB21585.1}.
FT DOMAIN 17..283
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 591..657
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 658..731
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 307..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..389
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 734 AA; 79009 MW; 76889318C1969F60 CRC64;
MSEAPHAPEG QVIEGRYRVV SRIADGGMAT VYQAVDERLG RTVAIKIMHT QLAQGPHRDQ
FVERFHREAR SAAAIANPHI VQVYDTGEFD GLDYLVMEYV HGVNLRYEMN QQGTFSVRET
LRIIGETLDG LASAHRAGVV HRDIKPENIL LNDRGHVQIT DFGLAKTVSQ ATLSSTGILL
GTAAYLAPEM IERNQATPQG DLYSVGIMAW EMLAGKVPFT SNNPVTLVFK HVHEDVPSIV
TVCEGINANV AAFIAHLTAR AVEARPADAS AALAELQRLQ SILAVSDWQY QLPAANVNIS
PNTTQAEDAA APMNEGNPAP PTPPAPPTQQ FDDRTRKLDR VKPNMTTVMP VQQQNVDPEA
TTRFSLPLDG DVNTADGSTR PQSPAMQNGD YGNAGKDESS KRHRTPLIVA GVAAFLLTCG
AGGWAWWCYQ GPGSYWTMPQ PDGMSCSDSV ACPITGVKWS DYESLLKVSD IEYEVSEKYS
DSITEGDIIS TDPANVGDRG SKRRGQKVKV VVSKGVRQAT VPADILDATS ASGKDPINAL
KKAGFDNVEQ TTASDDTYSM EVPQGALLSL SVDPGATLPH NTTITVTVSQ GPKPVTMPNI
VGKTKDEAQQ TMDDLKLTAN WTESFDDKIP QGQVISTSVS SGNTLHWGDS VDVVVSKGPE
TITLPNYVGQ KASDAKAALE KLGFTVKVSS QLTLNASQDK KVASQDPVGG TEVRIRDENG
TPTTITLKMY SSLF
//
