ID B6Y7U9_9RICK Unreviewed; 485 AA.
AC B6Y7U9;
DT 20-JAN-2009, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2009, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Trk system potassium uptake protein {ECO:0000256|PIRNR:PIRNR006247};
GN ORFNames=C1A_800 {ECO:0000313|EMBL:EEB55778.1};
OS Wolbachia endosymbiont of Culex quinquefasciatus JHB.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Wolbachieae; Wolbachia.
OX NCBI_TaxID=569881 {ECO:0000313|EMBL:EEB55778.1, ECO:0000313|Proteomes:UP000004540};
RN [1] {ECO:0000313|EMBL:EEB55778.1, ECO:0000313|Proteomes:UP000004540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|Proteomes:UP000004540};
RX PubMed=19114486; DOI=10.1128/JB.01731-08;
RA Salzberg S.L., Puiu D., Sommer D.D., Nene V., Lee N.H.;
RT "Genome sequence of the Wolbachia endosymbiont of Culex quinquefasciatus
RT JHB.";
RL J. Bacteriol. 191:1725-1725(2009).
CC -!- FUNCTION: Low-affinity potassium transport system. Interacts with Trk
CC system potassium uptake protein TrkA. {ECO:0000256|PIRNR:PIRNR006247}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|PIRNR:PIRNR006247}; Multi-pass membrane protein
CC {ECO:0000256|PIRNR:PIRNR006247}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TrkH potassium transport family.
CC {ECO:0000256|PIRNR:PIRNR006247}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEB55778.1}.
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DR EMBL; ABZA01000002; EEB55778.1; -; Genomic_DNA.
DR RefSeq; WP_007302604.1; NZ_DS996942.1.
DR AlphaFoldDB; B6Y7U9; -.
DR HOGENOM; CLU_030708_0_2_5; -.
DR Proteomes; UP000004540; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015379; F:potassium:chloride symporter activity; IEA:InterPro.
DR InterPro; IPR003445; Cat_transpt.
DR InterPro; IPR004772; TrkH.
DR PANTHER; PTHR32024:SF3; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR PANTHER; PTHR32024; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED; 1.
DR Pfam; PF02386; TrkH; 2.
DR PIRSF; PIRSF006247; TrkH; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|PIRNR:PIRNR006247};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR006247};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR006247};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006247};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR006247-1};
KW Potassium {ECO:0000256|ARBA:ARBA00022958, ECO:0000256|PIRNR:PIRNR006247};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538,
KW ECO:0000256|PIRNR:PIRNR006247};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006247}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT BINDING 110
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 111
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 219
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 313
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
FT BINDING 429
FT /ligand="K(+)"
FT /ligand_id="ChEBI:CHEBI:29103"
FT /evidence="ECO:0000256|PIRSR:PIRSR006247-1"
SQ SEQUENCE 485 AA; 53848 MW; AA6499164769B2AF CRC64;
MESLQVLRSI AFIVGIFLLL FGVAMLIPAI TNNYLGYEWK NFLVGFIVTC TFSAIFILLG
KLNRVHGMPA IFAITSCTWI ALSLFAAIPF YLDSLSYIDA LFEAVSGITT TGATVLSYIE
QQSPGILLWR AMLHGIGGFG VITVGIAIFP IFKVLSLNNL LYSEYSDALK RKLPHTRSVV
IHIAEIYYCL ILLCIFSYYL AGMPLFDAVC HGMSAVSTGG FANYNDSIGY YNNPILEVIT
IIFMILGSLP FLSYLKIIRR LDVCYDEQVS YFIKIVVISS LLACFWLYKN FDLGVFLSFR
YSTFTITSFI TSTGYVMCNY LNWSFISVLA FFLAFIGGCG GSASGGIKIF RLVIFLKSIR
NYFSSLLNPS ESDRVKLNGK ILENDEVQSV FTFFAIYMLT FAISSIVMSC LSNADFITSI
SSVSAMLTNS GPGFSNLIGP SGNYSSFSGG VKLFLSFLML LGRLEILPIY FCIGSLYWKL
CHSRV
//
