ID B7FUJ4_PHATC Unreviewed; 821 AA.
AC B7FUJ4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=CULlin protein 4 {ECO:0000313|EMBL:EEC50273.1};
GN Name=CUL1_2 {ECO:0000313|EMBL:EEC50273.1};
GN ORFNames=PHATRDRAFT_44571 {ECO:0000313|EMBL:EEC50273.1};
OS Phaeodactylum tricornutum (strain CCAP 1055/1).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae;
OC Phaeodactylum.
OX NCBI_TaxID=556484 {ECO:0000313|EMBL:EEC50273.1, ECO:0000313|Proteomes:UP000000759};
RN [1] {ECO:0000313|EMBL:EEC50273.1, ECO:0000313|Proteomes:UP000000759}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCAP 1055/1 {ECO:0000313|EMBL:EEC50273.1,
RC ECO:0000313|Proteomes:UP000000759};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
RN [2] {ECO:0000313|Proteomes:UP000000759}
RP GENOME REANNOTATION.
RC STRAIN=CCAP 1055/1 {ECO:0000313|Proteomes:UP000000759};
RG Diatom Consortium;
RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C.,
RA Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., Pitluck S.,
RA Rokhsar D., Bowler C.;
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; CM000607; EEC50273.1; -; Genomic_DNA.
DR RefSeq; XP_002178608.1; XM_002178572.1.
DR AlphaFoldDB; B7FUJ4; -.
DR STRING; 556484.B7FUJ4; -.
DR PaxDb; 2850-Phatr44571; -.
DR EnsemblProtists; Phatr3_J44571.t1; Phatr3_J44571.p1; Phatr3_J44571.
DR GeneID; 7197810; -.
DR KEGG; pti:PHATRDRAFT_44571; -.
DR eggNOG; KOG2167; Eukaryota.
DR HOGENOM; CLU_004747_7_2_1; -.
DR InParanoid; B7FUJ4; -.
DR OrthoDB; 36517at2759; -.
DR Proteomes; UP000000759; Chromosome 4.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF123; CULLIN-4; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000759};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 441..681
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 821 AA; 94624 MW; 8488260A4E58E508 CRC64;
MPRNKSLLKG GHTSRKIVIR PYSKPPTLPE NYYDDTVRSL LQSISEASSH RTFTGTAPSP
NSTGVSLQNA YKAVVYLVSH QYGPRLYRDL MDHMKQVAAR ILPEEREASA SRASLLMYIP
KQYQLYLEYL LLCKHVFLPL DRTHAWQPET KTVVVASTQT PGGLLTLWQV GLEMLQTRMQ
ELTLDRELYQ EWLAALLQDW NPASNNNLDA ANRQDLQSVW YLWQDLGQLA VLPLQEDLEE
YWKNQSQQMM EGYRAGSFLQ FAYDKHVHVT IWQPWLPSQW LRSVLENCFF QPHLNDQYLL
KPENLHPILQ SELFAIKTVV GVSSTAMEKL SSTQQLWTLA GRIAGGQRLV ATSIANFAKT
QGLACVQPAV ELSDGAGKAA AGQHILDKSP IPATNNVQIV SDLLDTQQRI SRLIQSLPHG
PELIILKNVW EEVLNVETTP ALAELLAKFL DQILRSNKKM DQYQSESEQW LQRIISGLFI
PLQAKDIFEA FYKRDLAKRL LWNRVVNMDV EKQVCSLLKA ECGAGFTSKM EGMFQDVDWS
RETMMVYKQS TADILPTENS VEMEAQVLTT GFLPRIPGYW PVYPQYPNLH LPESLKEPQE
RFGNHYKIKY QGRRMTWQYA LGHCVVRSSG FPKTYEFVVS LCQALVLIQF EEADTKLSLP
TLMQAIGLED RDEMERVLQS LALGKDGTRI LRKLDYDSEP NKKKKIRMNV DNRDEFTINR
KFESNQRRIR INNIMMKESK EEREKTVEAV SRDRLYLIDA VLVRIMKARK TILHQTLIPQ
VVEQVKVPAQ PGDIKQRIES LIEREYMERD AKDRNRYNYL A
//
