ID B7GC09_PHATC Unreviewed; 1164 AA.
AC B7GC09;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN ORFNames=PHATRDRAFT_49839 {ECO:0000313|EMBL:EEC43780.1};
OS Phaeodactylum tricornutum (strain CCAP 1055/1).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae;
OC Phaeodactylum.
OX NCBI_TaxID=556484 {ECO:0000313|EMBL:EEC43780.1, ECO:0000313|Proteomes:UP000000759};
RN [1] {ECO:0000313|EMBL:EEC43780.1, ECO:0000313|Proteomes:UP000000759}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCAP 1055/1 {ECO:0000313|EMBL:EEC43780.1,
RC ECO:0000313|Proteomes:UP000000759};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
RN [2] {ECO:0000313|Proteomes:UP000000759}
RP GENOME REANNOTATION.
RC STRAIN=CCAP 1055/1 {ECO:0000313|Proteomes:UP000000759};
RG Diatom Consortium;
RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C.,
RA Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., Pitluck S.,
RA Rokhsar D., Bowler C.;
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000627; EEC43780.1; -; Genomic_DNA.
DR RefSeq; XP_002184721.1; XM_002184685.1.
DR AlphaFoldDB; B7GC09; -.
DR PaxDb; 2850-Phatr49839; -.
DR EnsemblProtists; Phatr3_J49839.t1; Phatr3_J49839.p1; Phatr3_J49839.
DR GeneID; 7198567; -.
DR KEGG; pti:PHATRDRAFT_49839; -.
DR HOGENOM; CLU_274918_0_0_1; -.
DR InParanoid; B7GC09; -.
DR OrthoDB; 2695287at2759; -.
DR Proteomes; UP000000759; Chromosome 25.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF13374; TPR_10; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000759};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 374..484
FT /note="NACHT"
FT /evidence="ECO:0000259|Pfam:PF05729"
FT REPEAT 840..873
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1011..1044
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 298..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1164 AA; 130455 MW; AD5716779DEBBE6F CRC64;
MNEQSGISSD ESYAQDWVVE FEVIDEAAES ASHDAVPAAD QRHLQENVEE VAGLENSGVN
LVSNGSLPEE QQLQQQEQYP KAWHFGVSDG SDDPLNFLLS EDDSGVRAFG ISGSCIQPTE
PPESFSFNVE QKQAVETFLS GEAILQTPGN HVILGCRNFA PSPANHKFDH LLQQYWLDVR
AVEGALESRK RKTADVIEII HRHGDYFCFW DAHDGPRDDN GKLCSLSATT WQAFCFRRLE
SDKELKAKLR FPLETSLNRL TGRTHHQHSS SGASSVLAEQ GMGGISRPLM NLSIHAEREP
SDAAEEAVPA STRKRSIPKK SHLQKEASWK STLPSSNIHE IDSESEEPGV SEPLYGRYKE
MKDLKEKVSP DGKLVSLVGR SGVGKTHLAR VFAWEWTKER DKNCTRFGFW LNAATESTLR
ESYETAIRRL RHGTSLEEPS AKRRMVTIQS LALRLWETLA QLSLSFEWIL VFDNVPAFVE
ALDGTKREGP LGFQEWFLPR DWRNGRGRIL LLSTHDGYVG TTKSSMGYIA QIRVDLLDEE
SAVQMLQADL PEEQGSEASL HRLVSLFDCL PLAIATAKGE LLNDVISVDQ YIKRNNFDAV
QNRVQAAIRS SLNNAYQRGL GKVLDVAAYV NPDSIPLILL GGESANRAAI QLTKWNILRR
DWKTDSNEEV YSMHRLHQNA ARQVSLENGC SPGAALRVVH ENITTFDRDT PAHWKLPAAM
VKHVVALKER VESWPSELCF VWAQTLQKTA EVNRWVNHDF GGAKKMSHSC ISVCSSILKS
ECLLAEVREA VSEEMVKVHM FLGKLHRSCS QPDDAKESFD RARNLLRLCP ASDARSWLEA
DILDDIGRLE HNKSCYAQAL EHFRKALEIR YRAIPDSTRG ELVGSPFYSN DETYSTRLVE
QEALRDLGRN LLKSLLESAD TDVSLPKPQP VEREYSAQRK VLGALADTLV NFGRSYREGE
DCEGVQTWTK ENYGRSYGEN GYLEEALFWF EAALGAQSLQ FRNEIQNDSV ATTISHLGRV
HIAKGNFATG LEMFQKSLAM KQHVYGKEKG NESIATAWGN VATAKRLMGE CLVSEHRFEA
AFQCYTEAFE NYKRALGMLK SLFNDSNHKK VRETCAGIMS VANSVSLLTD LLIAMNDPDA
TLEINCRGLV ECCSNSISDQ QFEQ
//
