ID B7GCC8_PHATC Unreviewed; 1102 AA.
AC B7GCC8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN ORFNames=PHATRDRAFT_49932 {ECO:0000313|EMBL:EEC43842.1};
OS Phaeodactylum tricornutum (strain CCAP 1055/1).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae;
OC Phaeodactylum.
OX NCBI_TaxID=556484 {ECO:0000313|EMBL:EEC43842.1, ECO:0000313|Proteomes:UP000000759};
RN [1] {ECO:0000313|EMBL:EEC43842.1, ECO:0000313|Proteomes:UP000000759}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCAP 1055/1 {ECO:0000313|EMBL:EEC43842.1,
RC ECO:0000313|Proteomes:UP000000759};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
RN [2] {ECO:0000313|Proteomes:UP000000759}
RP GENOME REANNOTATION.
RC STRAIN=CCAP 1055/1 {ECO:0000313|Proteomes:UP000000759};
RG Diatom Consortium;
RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C.,
RA Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., Pitluck S.,
RA Rokhsar D., Bowler C.;
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM000627; EEC43842.1; -; Genomic_DNA.
DR RefSeq; XP_002184783.1; XM_002184747.1.
DR AlphaFoldDB; B7GCC8; -.
DR STRING; 556484.B7GCC8; -.
DR PaxDb; 2850-Phatr49932; -.
DR EnsemblProtists; Phatr3_J49932.t1; Phatr3_J49932.p1; Phatr3_J49932.
DR GeneID; 7198629; -.
DR KEGG; pti:PHATRDRAFT_49932; -.
DR eggNOG; KOG0211; Eukaryota.
DR HOGENOM; CLU_283062_0_0_1; -.
DR InParanoid; B7GCC8; -.
DR OMA; YCRICAT; -.
DR OrthoDB; 1367932at2759; -.
DR Proteomes; UP000000759; Chromosome 25.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR10648; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10648:SF1; SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 3.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000759};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 134..171
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 236..274
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 579..616
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 962..1024
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 907..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1034..1102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 927..941
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1055
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1070..1093
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1102 AA; 122259 MW; BD08018D2F8624DF CRC64;
MEAANSANEA VVEVDDDAVR FEDLTVDDDL PILERVVRYS RSQIALQRLV HVKMLAETAE
IVGQRSTQEV LIPLLRSLVS DPESIIRQHV STQLVPVCIV CMVKNVSNVA ELVQNPVFSK
DYDEKGYTLV TTTVLGHINT LLEDFDLDVR RAAADALSGL ALQIRPADVP QALLQIPLAL
AAKLPKNPHA KKKTEADQHV EELRITAGNL LAELGGAASE HSTTLLASST YVSGLILPAV
LKLCDDVSFR VRRSAAQALP RILGACSLND VEETILPAFD QLSRDDLYRV RKSTGECLVD
MSRSMMLLAA SNKKAERTLY KLRRETLIPI ADRLIQDSHK MVRQGMMQFL GPFMASFYPY
QTSALRDLLP GTVESDGSNH MGIVAQFFPH ATSMVSRLNS AQNISMSAPT PVNVHLDEIL
HRVLSEMDVL HQALPAFLQA SRMSALSLAA VATHRNRNLP DSEDVDVLID KLLDYFAALA
IVSTGDENTD AEMRVYCAYS FPALILLLGA DNWEGAMRTC FFTLMNPNYA KTQQPEEKQS
DPAENLNVAE PPLPVKRCLA SSLHTVANIL GPELAASDIV PVLQDFFLKD PDESVRLNVI
RNFPALLQVL SPSDRKGPFL MWSEIVRGEE LLGIKKRSAH NPVVLNWRQR DYLARSLPDL
IGLVEPSLVH EHIWPIMKTL LTDAVSIVRD DAIWSIAMIL KAYCLESLQA WPNVSNFRAF
GAQSCAEVID WLKESILKLG VPREARIKPV NFSERQLYCR ICATLGLALR FSEQIEGDKQ
DPVSVLSGKF KTFFFPKSKN LQDDLPGPYQ AMTKSEQKHL RRLLLNELLP PALEMKEDRI
SNVRVSLMKT LQLMPAEIRA TPLVQPVLQG LVEEVETWEN FAISDQPVPN PLKQSASQAA
LYQPAQRSLA SGAVSPRAQQ SVPVDLDAEM PDDRRSSSDD SSASAEDVAE SSDWKTVVFQ
AGPIGMQLEP TADDRACRVY GFLDSGDGKP SPARHSGKIE LGDVIVKVNG KDVHSYDDTI
AVLKAGGRRE ITFRQGTADD DYDDDEEEES VGGFSSTDDE TDRKERERKA KKEAKKAKKA
KKETKKKSRD KKKDKRKKEE TG
//
