ID B7INX8_BACC2 Unreviewed; 279 AA.
AC B7INX8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Oxidoreductase, aldo/keto reductase family {ECO:0000313|EMBL:ACK97384.1};
GN OrderedLocusNames=BCG9842_B0038 {ECO:0000313|EMBL:ACK97384.1};
OS Bacillus cereus (strain G9842).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=405531 {ECO:0000313|EMBL:ACK97384.1, ECO:0000313|Proteomes:UP000006744};
RN [1] {ECO:0000313|EMBL:ACK97384.1, ECO:0000313|Proteomes:UP000006744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G9842 {ECO:0000313|EMBL:ACK97384.1,
RC ECO:0000313|Proteomes:UP000006744};
RA Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA Ravel J., Sutton G.;
RT "Genome sequence of Bacillus cereus G9842.";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001186; ACK97384.1; -; Genomic_DNA.
DR RefSeq; WP_000793558.1; NC_011772.1.
DR AlphaFoldDB; B7INX8; -.
DR KEGG; bcg:BCG9842_B0038; -.
DR HOGENOM; CLU_023205_0_1_9; -.
DR Proteomes; UP000006744; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd19157; AKR_AKR5G1-3; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR044500; AKR5G.
DR InterPro; IPR018170; Aldo/ket_reductase_CS.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43827; 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE; 1.
DR PANTHER; PTHR43827:SF1; 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PIRSF; PIRSF000097; AKR; 2.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00798; ALDOKETO_REDUCTASE_1; 1.
DR PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
DR PROSITE; PS00063; ALDOKETO_REDUCTASE_3; 1.
PE 4: Predicted;
FT DOMAIN 30..266
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
FT ACT_SITE 53
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-1"
FT BINDING 115
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-2"
FT SITE 82
FT /note="Lowers pKa of active site Tyr"
FT /evidence="ECO:0000256|PIRSR:PIRSR000097-3"
SQ SEQUENCE 279 AA; 31812 MW; 83490AD64B345287 CRC64;
MKNLQSKTVL NNGVEMPWFG LGVFKVEEGP ELVEAVKSAI KAGYRSIDTA AIYGNEKAVG
EGIRAGIEAT GISREELFIT SKVWNADQGY EETIAAYEES LKKLELDYLD LYLVHWPVEG
KYKDTWRALE TLYKEDRVRA IGVSNFQIHH LQDVMKDAEI KPMINQVEYH PRLTQKELQA
FCKEQGIQME AWSPLMQGQL LDNETLQAIA EKHGKTTAQV ILRWDLQNGI ITIPKSTKEH
RIIANADVFN FELTKEDMET IDALNENHRV GPDPDNFDF
//
