ID NUOC_ACIF2 Reviewed; 202 AA.
AC B7J7U3;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 29-MAY-2013, entry version 31.
DE RecName: Full=NADH-quinone oxidoreductase subunit C;
DE EC=1.6.99.5;
DE AltName: Full=NADH dehydrogenase I subunit C;
DE AltName: Full=NDH-1 subunit C;
GN Name=nuoC; OrderedLocusNames=AFE_2628;
OS Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB
OS 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Acidithiobacillales;
OC Acidithiobacillaceae; Acidithiobacillus.
OX NCBI_TaxID=243159;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23270 / DSM 14882 / NCIB 8455;
RX PubMed=19077236; DOI=10.1186/1471-2164-9-597;
RA Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H.,
RA Blake R. II, Eisen J.A., Holmes D.S.;
RT "Acidithiobacillus ferrooxidans metabolism: from genome sequence to
RT industrial applications.";
RL BMC Genomics 9:597-597(2008).
CC -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-
CC sulfur (Fe-S) centers, to quinones in the respiratory chain. The
CC immediate electron acceptor for the enzyme in this species is
CC believed to be ubiquinone. Couples the redox reaction to proton
CC translocation (for every two electrons transferred, four hydrogen
CC ions are translocated across the cytoplasmic membrane), and thus
CC conserves the redox energy in a proton gradient (By similarity).
CC -!- CATALYTIC ACTIVITY: NADH + quinone = NAD(+) + quinol.
CC -!- SUBUNIT: NDH-1 is composed of 14 different subunits. Subunits
CC NuoB, C, D, E, F, and G constitute the peripheral sector of the
CC complex (By similarity).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane
CC protein; Cytoplasmic side (By similarity).
CC -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
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DR EMBL; CP001219; ACK79369.1; -; Genomic_DNA.
DR RefSeq; YP_002427006.1; NC_011761.1.
DR STRING; 243159.AFE_2628; -.
DR EnsemblBacteria; ACK79369; ACK79369; AFE_2628.
DR GeneID; 7135259; -.
DR KEGG; afr:AFE_2628; -.
DR PATRIC; 20656267; VBIAciFer29821_2388.
DR eggNOG; COG0852; -.
DR HOGENOM; HOG000009799; -.
DR KO; K00332; -.
DR OMA; GLVFEGH; -.
DR ProtClustDB; CLSK2408393; -.
DR BioCyc; AFER243159:GH3S-2623-MONOMER; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR GO; GO:0019684; P:photosynthesis, light reaction; IEA:HAMAP.
DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR HAMAP; MF_01357; NDH1_NuoC; 1; -.
DR InterPro; IPR010218; NADH_DH_suC.
DR InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR Pfam; PF00329; Complex1_30kDa; 1.
DR ProDom; PD001581; NADH_UbQ_OxRdtase_30kDa_su; 1.
DR TIGRFAMs; TIGR01961; NuoC_fam; 1.
DR PROSITE; PS00542; COMPLEX1_30K; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Complete proteome; Membrane; NAD;
KW Oxidoreductase; Quinone; Transport; Ubiquinone.
FT CHAIN 1 202 NADH-quinone oxidoreductase subunit C.
FT /FTId=PRO_1000143678.
SQ SEQUENCE 202 AA; 23107 MW; 738E2E4F8DD962AC CRC64;
MTDALENLRQ HLSDELGATL RTAHLDRGEL TVELSREGFP AACLLLRDDV ACAFDLLVDV
CGVDYSAYGE GLWEGPRFAV VYHLLSLKHR QRLRVRIFAD DDLPIVPSVV EVWAAANWFE
REAFDLYGIL FDGHPDLRRI LTDYGFVGHP FRKDFPLVGT VEMRYDADQG RVVYEPTRTE
ERVVVPRIIR EAGEGRYNAR NQ
//
