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Database: UniProt
Entry: B7J7U3
LinkDB: B7J7U3
Original site: B7J7U3 
ID   NUOC_ACIF2              Reviewed;         202 AA.
AC   B7J7U3;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   19-FEB-2014, entry version 34.
DE   RecName: Full=NADH-quinone oxidoreductase subunit C;
DE            EC=1.6.99.5;
DE   AltName: Full=NADH dehydrogenase I subunit C;
DE   AltName: Full=NDH-1 subunit C;
GN   Name=nuoC; OrderedLocusNames=AFE_2628;
OS   Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB
OS   8455) (Ferrobacillus ferrooxidans (strain ATCC 23270)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=243159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23270 / DSM 14882 / NCIB 8455;
RX   PubMed=19077236; DOI=10.1186/1471-2164-9-597;
RA   Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H.,
RA   Blake R. II, Eisen J.A., Holmes D.S.;
RT   "Acidithiobacillus ferrooxidans metabolism: from genome sequence to
RT   industrial applications.";
RL   BMC Genomics 9:597-597(2008).
CC   -!- FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-
CC       sulfur (Fe-S) centers, to quinones in the respiratory chain. The
CC       immediate electron acceptor for the enzyme in this species is
CC       believed to be ubiquinone. Couples the redox reaction to proton
CC       translocation (for every two electrons transferred, four hydrogen
CC       ions are translocated across the cytoplasmic membrane), and thus
CC       conserves the redox energy in a proton gradient (By similarity).
CC   -!- CATALYTIC ACTIVITY: NADH + quinone = NAD(+) + quinol.
CC   -!- SUBUNIT: NDH-1 is composed of 14 different subunits. Subunits
CC       NuoB, C, D, E, F, and G constitute the peripheral sector of the
CC       complex (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane
CC       protein; Cytoplasmic side (By similarity).
CC   -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
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DR   EMBL; CP001219; ACK79369.1; -; Genomic_DNA.
DR   RefSeq; YP_002427006.1; NC_011761.1.
DR   STRING; 243159.AFE_2628; -.
DR   EnsemblBacteria; ACK79369; ACK79369; AFE_2628.
DR   GeneID; 7135259; -.
DR   KEGG; afr:AFE_2628; -.
DR   PATRIC; 20656267; VBIAciFer29821_2388.
DR   eggNOG; COG0852; -.
DR   HOGENOM; HOG000009799; -.
DR   KO; K00332; -.
DR   OMA; LVFEGHP; -.
DR   OrthoDB; EOG60PHFK; -.
DR   ProtClustDB; CLSK2408393; -.
DR   BioCyc; AFER243159:GH3S-2623-MONOMER; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   HAMAP; MF_01357; NDH1_NuoC; 1.
DR   InterPro; IPR010218; NADH_DH_suC.
DR   InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR   InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR   Pfam; PF00329; Complex1_30kDa; 1.
DR   ProDom; PD001581; NADH_UbQ_OxRdtase_30kDa_su; 1.
DR   TIGRFAMs; TIGR01961; NuoC_fam; 1.
DR   PROSITE; PS00542; COMPLEX1_30K; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane; NAD;
KW   Oxidoreductase; Quinone; Transport; Ubiquinone.
FT   CHAIN         1    202       NADH-quinone oxidoreductase subunit C.
FT                                /FTId=PRO_1000143678.
SQ   SEQUENCE   202 AA;  23107 MW;  738E2E4F8DD962AC CRC64;
     MTDALENLRQ HLSDELGATL RTAHLDRGEL TVELSREGFP AACLLLRDDV ACAFDLLVDV
     CGVDYSAYGE GLWEGPRFAV VYHLLSLKHR QRLRVRIFAD DDLPIVPSVV EVWAAANWFE
     REAFDLYGIL FDGHPDLRRI LTDYGFVGHP FRKDFPLVGT VEMRYDADQG RVVYEPTRTE
     ERVVVPRIIR EAGEGRYNAR NQ
//
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