ID B7LCV1_ECO55 Unreviewed; 315 AA.
AC B7LCV1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=TreR protein {ECO:0000313|EMBL:CAV01769.1};
GN Name=treR {ECO:0000313|EMBL:CAV01769.1};
GN OrderedLocusNames=EC55989_4799 {ECO:0000313|EMBL:CAV01769.1};
OS Escherichia coli (strain 55989 / EAEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585055 {ECO:0000313|EMBL:CAV01769.1, ECO:0000313|Proteomes:UP000000746};
RN [1] {ECO:0000313|Proteomes:UP000000746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=55989 / EAEC {ECO:0000313|Proteomes:UP000000746};
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
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DR EMBL; CU928145; CAV01769.1; -; Genomic_DNA.
DR RefSeq; WP_001181324.1; NZ_CP028304.1.
DR AlphaFoldDB; B7LCV1; -.
DR SMR; B7LCV1; -.
DR GeneID; 75203537; -.
DR KEGG; eck:EC55989_4799; -.
DR HOGENOM; CLU_037628_9_0_6; -.
DR Proteomes; UP000000746; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01542; PBP1_TreR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR012771; Trehalos_R_gpbac.
DR NCBIfam; TIGR02405; trehalos_R_Ecol; 1.
DR PANTHER; PTHR30146:SF153; HTH-TYPE TRANSCRIPTIONAL REGULATOR TRER; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000746};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..59
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 315 AA; 34574 MW; 20C2B0F2584D34BA CRC64;
MQNRLTIKDI ARLSGVGKST VSRVLNNESG VSQRTRERVE AVMNQHGFSP SRSARAMRGQ
SDKVVAIIVT RLDSLSENLA VQTMLPAFYE QGYDPIMMES QFSPQLVAEH LGVLKRRNID
GVVLFGFTGI TEEMLAHWQS SLVLLARDAK GFASVCYDDE GAIKILMQRL YDQGHRNISY
LGVPHSDVTT GKRRHEAYLA FCKAHKLHPV AALPGLAMKQ GYENVAKVIT PETTALLCAT
DTLALGASKY LQEQRIDTLQ LASVGNTPLM KFLHPEIVTV DPGYAEAGRQ AACQLIAQVT
GRSEPQQIII PATLS
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