ID   B7MIB6_ECO45            Unreviewed;       684 AA.
AC   B7MIB6;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   01-MAY-2013, entry version 31.
DE   SubName: Full=DNA helicase IV;
DE            EC=3.6.1.-;
GN   Name=helD; OrderedLocusNames=ECS88_0984;
OS   Escherichia coli O45:K1 (strain S88 / ExPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585035;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S88 / ExPEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A.,
RA   Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M.,
RA   Dossat C., Karoui M.E., Frapy E., Garry L., Ghigo J.M., Gilles A.M.,
RA   Johnson J., Le Bouguenec C., Lescat M., Mangenot S.,
RA   Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A.,
RA   Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B.,
RA   Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
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DR   EMBL; CU928161; CAR02316.1; -; Genomic_DNA.
DR   RefSeq; YP_002390774.1; NC_011742.1.
DR   ProteinModelPortal; B7MIB6; -.
DR   STRING; 585035.ECS88_0984; -.
DR   EnsemblBacteria; CAR02316; CAR02316; ECS88_0984.
DR   GeneID; 7130164; -.
DR   KEGG; ecz:ECS88_0984; -.
DR   PATRIC; 18409689; VBIEscCol91599_0986.
DR   eggNOG; COG0210; -.
DR   HOGENOM; HOG000118816; -.
DR   KO; K03658; -.
DR   OMA; VSPWKHI; -.
DR   ProtClustDB; PRK11054; -.
DR   BioCyc; ECOL585035:GJWP-986-MONOMER; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR022161; Helicase_IV_N.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070; PTHR11070; 1.
DR   Pfam; PF12462; Nucleolin_N; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase;
KW   Nucleotide-binding.
SQ   SEQUENCE   684 AA;  77968 MW;  B893B0E759501ECC CRC64;
     MELKATTLGK RLAQHPYDRA VILNAGIKVS GDRHEYLIPF NQLLAIHCKR GLVWGELEFV
     LPDEKVVRLH GTEWGETQRF YHHLDAHWRR WSGEMSEIAS GVLRQQLDLI ATRTGENKWL
     TREQTSGVQQ QIRQALSALP LPVNRLEEFD NCREVWRKCQ AWLKDIEGAR LQHNQAYTEA
     MLTEYADFFR QVESSPLNPA QARAVVNGEH SLLVLAGAGS GKTSVLVARA GWLLARGEAS
     PEQILLLAFG RKAAEEMHER IRERLHTEDI TARTFHALAL HIIQQGSKKV PIVSKLENDT
     AARHELFIAE WRKQCSEKKA QAKGWRQWLT EEMQWSVPEG NFWDDEKLQR RLASRLDRWV
     SLMRMHGGAQ AEMIASAPEE IRDLFSKRIK LMAPLLKAWK GALKAENTVD FSGLIHQAIV
     ILEKGRFISP WKHILVDEFQ DISPQRAALL AALRKQNSQT TLFAVGDDWQ AIYRFSGAQM
     SLTTAFHENF GEGDRCDLDT TYRFNSRIGE VANRFIQQNP GQLKKPLNSL TNGDKKAVTL
     LDEGQLDALL DKLSGYAKPE ERILILARYH HMRPASLEKA ATRWPKLQID FMTIHASKGQ
     QADYVIIVGL QEGSDGFPAA ARESIMEEAL LPPVEDFPDA EERRLMYVAL TRARHRVWAL
     FNKENPSPFV DILKNLDVPV ARKP
//