ID   B7MQ95_ECO81            Unreviewed;       277 AA.
AC   B7MQ95;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:CAR06507.1};
GN   OrderedLocusNames=ECED1_0293 {ECO:0000313|EMBL:CAR06507.1};
OS   Escherichia coli O81 (strain ED1a).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585397 {ECO:0000313|EMBL:CAR06507.1, ECO:0000313|Proteomes:UP000000748};
RN   [1] {ECO:0000313|Proteomes:UP000000748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ED1a {ECO:0000313|Proteomes:UP000000748};
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
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DR   EMBL; CU928162; CAR06507.1; -; Genomic_DNA.
DR   RefSeq; WP_000033841.1; NC_011745.1.
DR   AlphaFoldDB; B7MQ95; -.
DR   KEGG; ecq:ECED1_0293; -.
DR   HOGENOM; CLU_055769_1_3_6; -.
DR   Proteomes; UP000000748; Chromosome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05013; SIS_RpiR; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR000281; HTH_RpiR.
DR   InterPro; IPR047640; RpiR-like.
DR   InterPro; IPR035472; RpiR-like_SIS.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR30514; GLUCOKINASE; 1.
DR   PANTHER; PTHR30514:SF20; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   Pfam; PF01418; HTH_6; 1.
DR   Pfam; PF01380; SIS; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF53697; SIS domain; 1.
DR   PROSITE; PS51071; HTH_RPIR; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   4: Predicted;
FT   DOMAIN          9..85
FT                   /note="HTH rpiR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51071"
FT   DOMAIN          141..277
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
SQ   SEQUENCE   277 AA;  30819 MW;  2FB4EFCFA7BEC387 CRC64;
     MSKHQTQLSL LQDDIRSRYD SLSKRLKQVA QYILDNSNSV AFDTVASIAQ HADVPPSTLI
     RFANAFGFSG FNEMKRIFRQ HLMEETVSYT ERARLFRQKN ADEGEPTPEK PGEILKLFSM
     VNAQVLQQLP VQIKNEQLDA AVNLLAKADN IYVIGLRRSF SVASYLTYAL RHLERRAFLI
     DGIGGMFSEQ LSMVSSDDVV IAISYSPYAQ EVVELVELGA KRGAHYIAIT DSQVSPLAAF
     SEVCFVVREA QVDGFRSQVA SMCLAQTLAV SLALATE
//