ID   B7MUU8_ECO81            Unreviewed;       297 AA.
AC   B7MUU8;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=DNA-binding transcriptional regulator {ECO:0000313|EMBL:CAR07864.1};
GN   Name=ynfL {ECO:0000313|EMBL:CAR07864.1};
GN   OrderedLocusNames=ECED1_1764 {ECO:0000313|EMBL:CAR07864.1};
OS   Escherichia coli O81 (strain ED1a).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585397 {ECO:0000313|EMBL:CAR07864.1, ECO:0000313|Proteomes:UP000000748};
RN   [1] {ECO:0000313|Proteomes:UP000000748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ED1a {ECO:0000313|Proteomes:UP000000748};
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU928162; CAR07864.1; -; Genomic_DNA.
DR   RefSeq; WP_001019562.1; NC_011745.1.
DR   AlphaFoldDB; B7MUU8; -.
DR   KEGG; ecq:ECED1_1764; -.
DR   HOGENOM; CLU_039613_6_4_6; -.
DR   Proteomes; UP000000748; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08414; PBP2_LTTR_aromatics_like; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF17; LYSR FAMILY TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000313|EMBL:CAR07864.1}.
FT   DOMAIN          3..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   297 AA;  33389 MW;  79EE0914FBD31C3C CRC64;
     MNIELRHLRY FVAVAEELHF GRAAARLNIS QPPLSQQIQA LEQQIGARLL ARTNRSVLLT
     EAGKQFLVDS RQILSMVDDA AARAERLHQG EAGELRIGFT SSAPFIRAVS DTLSLFRRDY
     PDVHLQTREM NTREQIAPLI EGTLDMGLLR NTELPETLEH AVIVHEPLMA MIPHDHPLAN
     NPSVTLAELA KEPFVFFDPH VGTGLYDDIL GLMRRYNLTP VITQEVGEAM TIIGLVSAGL
     GVSILPASFK RVQLNEMRWV PIAEEDAVSE MWLVWPKHHE QSPAARNFRI HLLNALR
//