ID B7P7G0_IXOSC Unreviewed; 370 AA.
AC B7P7G0;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
GN ORFNames=IscW_ISCW015953 {ECO:0000313|EMBL:EEC02532.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC02532.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC02532.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW015953-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW015953-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663, ECO:0000256|RuleBase:RU000688}.
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DR EMBL; ABJB010153156; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS651746; EEC02532.1; -; Genomic_DNA.
DR RefSeq; XP_002410128.1; XM_002410084.1.
DR AlphaFoldDB; B7P7G0; -.
DR STRING; 6945.B7P7G0; -.
DR PaxDb; 6945-B7P7G0; -.
DR EnsemblMetazoa; ISCW015953-RA; ISCW015953-PA; ISCW015953.
DR KEGG; isc:IscW_ISCW015953; -.
DR VEuPathDB; VectorBase:ISCI018273; -.
DR VEuPathDB; VectorBase:ISCP_004318; -.
DR VEuPathDB; VectorBase:ISCW015953; -.
DR HOGENOM; CLU_050919_0_0_1; -.
DR InParanoid; B7P7G0; -.
DR OMA; CHPIKFF; -.
DR OrthoDB; 3019460at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd14978; 7tmA_FMRFamide_R-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR47760; G-PROTEIN COUPLED RECEPTOR B0563.6-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR47760:SF1; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..330
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 370 AA; 41714 MW; FBB83B46FB4FC40F CRC64;
MVVCPNVKPV LVNESSPSSE PLIVQYRFEN DEETLILKQQ IDTLKFIAYG VVSFVIIALG
IVGNLINLIV LTRPNLKGVT FVYLTWLATS DLLTLVVAVF SMLRLHGIQP RTYPAAFYFA
HVEMPLVNAL MASSVFIVVA VTIDRYWSVC LPLRYREFHN SRCTKLAIIT AYVAAGLLYV
PVAFQKSPVP VWDELANQTQ YIPCDNVYVS RQPVFKIYLL VKEVLVRIGP VLVVAVLNTT
IIVTFHRFVR KRQKLMSNSS NRDTGKVLED QRLVILLAAI VIMFCVCMTP AAVLTVLISD
DKELNYGFQL FRAIANDMEM ANFAMNFYVY CLCSSEIRDT FLRLFRLSKS SPDVSYILNS
KSPADGSTHL
//
