ID B7P9Z1_IXOSC Unreviewed; 605 AA.
AC B7P9Z1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=F-box and WD domain protein, putative {ECO:0000313|EMBL:EEC03413.1, ECO:0000313|EnsemblMetazoa:ISCW017325-PA};
DE EC=2.7.11.7 {ECO:0000313|EMBL:EEC03413.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW017325 {ECO:0000313|EMBL:EEC03413.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC03413.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC03413.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW017325-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW017325-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010013381; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010035035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010099054; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010384579; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010479608; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010861906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011065340; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS668046; EEC03413.1; -; Genomic_DNA.
DR RefSeq; XP_002405857.1; XM_002405813.1.
DR AlphaFoldDB; B7P9Z1; -.
DR STRING; 6945.B7P9Z1; -.
DR PaxDb; 6945-B7P9Z1; -.
DR EnsemblMetazoa; ISCW017325-RA; ISCW017325-PA; ISCW017325.
DR KEGG; isc:IscW_ISCW017325; -.
DR VEuPathDB; VectorBase:ISCI017325; -.
DR VEuPathDB; VectorBase:ISCP_013653; -.
DR VEuPathDB; VectorBase:ISCW017325; -.
DR HOGENOM; CLU_000288_103_7_1; -.
DR InParanoid; B7P9Z1; -.
DR OMA; AMVPWED; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR GO; GO:0016905; F:myosin heavy chain kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0030621; F:U4 snRNA binding; IBA:GO_Central.
DR GO; GO:0017070; F:U6 snRNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd22133; F-box_FBXW7; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 1.10.150.280; AF1531-like domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19849; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR19849:SF3; PROTEIN WITH WD-40 REPEAT DOMAIN; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF12836; HHH_3; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 5.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:EEC03413.1};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 172..218
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 275..315
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 316..355
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 356..395
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 396..435
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 436..475
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 476..515
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 519..558
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 68..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..82
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC03413.1"
SQ SEQUENCE 605 AA; 66657 MW; 357B848A0FCA1A26 CRC64;
ALVDVNTCTI GDLAQVAGVC RATAEAIVAA RKLQGGFSCL EDLGGVPGVG PSLLETLQLC
LTCSPKERTH DPLGHRPCKK PCSREAVPGS GRSSPLPVGA ESPPSEEQES PPARRSRHPS
TLVQPPHLDA WLTTFQSWTH LERLCALDQL IEACEPGQVR HMMHVIEPQF QRDFISLLPK
ELALYVLSFL EPRDLLRAAQ TCHYWRILAE DNLLWREKCR EAGLEDVKEV LGRRVASPPS
PGGVPPPIPW KLAFMRHHYV EMNWRCKPIR EPKVLRGHED HVITCLQFSG NRIVSGSDDN
TLKVWSASSG RCLRTLVGHT GGVWSSQMAG SLVVSGSTDR TLRVWDADTG HCLHTLYGHT
STVRCMHLCA NRVVSGSRDA TLRVWDLETG ECLHVLVGHV AAVRCVQYNG RLVVSGAYDY
MVKVWDPRRE ECLHTLQGHT NRVYSLQFDG VHVVSGSLDT SIRVWDVETG ACRHQLMGHQ
SLTSGMELRN NILVSGNADS TVKVWDILTG QCLQTLAGAN KHQSAVTCLQ FNSKFVVTSS
DDGTVKLWDL RTGEFLRNLV ALESGGSGGV VWRLRASPTK LVCAVGSRNG TEETKLLVLD
FDEPK
//
