ID B7PAI1_IXOSC Unreviewed; 577 AA.
AC B7PAI1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 79.
DE SubName: Full=Acetylcholine regulator unc-18, putative {ECO:0000313|EMBL:EEC03603.1, ECO:0000313|EnsemblMetazoa:ISCW002599-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW002599 {ECO:0000313|EMBL:EEC03603.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC03603.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC03603.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW002599-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW002599-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC {ECO:0000256|ARBA:ARBA00009884}.
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DR EMBL; ABJB010023099; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010427788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011066736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS671232; EEC03603.1; -; Genomic_DNA.
DR RefSeq; XP_002406866.1; XM_002406822.1.
DR AlphaFoldDB; B7PAI1; -.
DR STRING; 6945.B7PAI1; -.
DR PaxDb; 6945-B7PAI1; -.
DR EnsemblMetazoa; ISCW002599-RA; ISCW002599-PA; ISCW002599.
DR KEGG; isc:IscW_ISCW002599; -.
DR VEuPathDB; VectorBase:ISCI002599; -.
DR VEuPathDB; VectorBase:ISCP_006394; -.
DR VEuPathDB; VectorBase:ISCW002599; -.
DR HOGENOM; CLU_009210_2_0_1; -.
DR InParanoid; B7PAI1; -.
DR OMA; RNQYKCA; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0098793; C:presynapse; IEA:GOC.
DR GO; GO:0030141; C:secretory granule; IBA:GO_Central.
DR GO; GO:0019905; F:syntaxin binding; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0007269; P:neurotransmitter secretion; IBA:GO_Central.
DR GO; GO:0006904; P:vesicle docking involved in exocytosis; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 1.25.40.60; -; 1.
DR Gene3D; 3.40.50.1910; -; 1.
DR Gene3D; 3.40.50.2060; -; 1.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR043127; Sec-1-like_dom3a.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR PANTHER; PTHR11679:SF30; PROTEIN ROP; 1.
DR PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR Pfam; PF00995; Sec1; 1.
DR PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PAI1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC03603.1"
SQ SEQUENCE 577 AA; 66277 MW; BAF0E1F56B54B791 CRC64;
EITNDVIRTV KKKGEWKVLV VDQLGMRMIS ACCKMHELAS EGITIVEDLS KKREPLPNIE
AVYLITPTEK SIRLLMADFQ TPTRHMYRCA HIFFTEKCPD ELFTEICKSP MAKVIKTLKE
VNIAFLPYES QIFSLDTPET FQFYYNPNRI NERASNLERI AEQVATLCAT LGEYPSLRYR
SDFDHNVELT QLIYQKLDAY KADEPTMGEG PEKMRSQLII LDRGFDCVSP LLHELTFQAM
AYDLLPIEND VYKFESTSGN DVREKEVLLD EKDDLWVELR HQHIAVVAVT KQLKKFIESK
RMTSSGDKAS LKDLTTMIKK MPQYQKELSK YSTQLHLAED CMKSYQGCVD RLCKVEQDLA
MGTDAEGEKI KDPMRNIVPI LLDTTVSNFD KIRIILLYIL SKNGISEENL TKLIQHAQIP
ATEKCIITNM AHLGVNIVTD GSRKKVYHVT RKERITEQTY QMSRWTPVMK DIMEDAIEDK
LDVKHFPFLS GGRVVPTGYG RSAPTSQRYG HWHKDKNTPN VKNVPRLMVF VIGGITYSEM
RCAYEVTKDA KNWEVIIGSD HILTPEGFLS DLRDLSN
//
