ID B7PCZ0_IXOSC Unreviewed; 158 AA.
AC B7PCZ0;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Glutamate receptor, metabotropic, putative {ECO:0000313|EMBL:EEC04462.1, ECO:0000313|EnsemblMetazoa:ISCW002379-PA};
GN ORFNames=IscW_ISCW002379 {ECO:0000313|EMBL:EEC04462.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC04462.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC04462.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW002379-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW002379-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010798517; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS686939; EEC04462.1; -; Genomic_DNA.
DR RefSeq; XP_002410449.1; XM_002410404.1.
DR AlphaFoldDB; B7PCZ0; -.
DR STRING; 6945.B7PCZ0; -.
DR PaxDb; 6945-B7PCZ0; -.
DR EnsemblMetazoa; ISCW002379-RA; ISCW002379-PA; ISCW002379.
DR KEGG; isc:IscW_ISCW002379; -.
DR VEuPathDB; VectorBase:ISCI002379; -.
DR VEuPathDB; VectorBase:ISCP_029721; -.
DR VEuPathDB; VectorBase:ISCW002379; -.
DR HOGENOM; CLU_1671256_0_0_1; -.
DR InParanoid; B7PCZ0; -.
DR OMA; RSEECIC; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF176; MANGETOUT, ISOFORM G; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000313|EMBL:EEC04462.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..158
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010826029"
FT DOMAIN 84..137
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
SQ SEQUENCE 158 AA; 17449 MW; B3A87885A87962C2 CRC64;
MERALTRPAP WRPLPWQQAG LFLLVLAVLA GPGPGSTASL NFTWPVKRAV VVDGDVVLGA
LMMVHEREDR LTCGRIMPQG GIQALECMLF TLDWVNQQPD ILPGFNLGAY VLDDCDKDTY
GLEQAVDFIK GECRQRVRRA RFGGKGLARG DPVAPFDR
//
