ID B7PEY2_IXOSC Unreviewed; 279 AA.
AC B7PEY2;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Sorting nexin, putative {ECO:0000313|EMBL:EEC05154.1, ECO:0000313|EnsemblMetazoa:ISCW018037-PA};
GN Name=8050473 {ECO:0000313|EnsemblMetazoa:ISCW018037-PA};
GN ORFNames=IscW_ISCW018037 {ECO:0000313|EMBL:EEC05154.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC05154.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC05154.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW018037-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW018037-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010531824; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS698527; EEC05154.1; -; Genomic_DNA.
DR RefSeq; XP_002433754.1; XM_002433709.1.
DR AlphaFoldDB; B7PEY2; -.
DR STRING; 6945.B7PEY2; -.
DR PaxDb; 6945-B7PEY2; -.
DR EnsemblMetazoa; ISCW018037-RA; ISCW018037-PA; ISCW018037.
DR GeneID; 8050473; -.
DR KEGG; isc:IscW_ISCW018037; -.
DR VEuPathDB; VectorBase:ISCI018037; -.
DR VEuPathDB; VectorBase:ISCP_025010; -.
DR VEuPathDB; VectorBase:ISCW018037; -.
DR HOGENOM; CLU_998467_0_0_1; -.
DR InParanoid; B7PEY2; -.
DR OrthoDB; 2899602at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005769; C:early endosome; IBA:GO_Central.
DR GO; GO:0031313; C:extrinsic component of endosome membrane; IBA:GO_Central.
DR GO; GO:0005770; C:late endosome; IBA:GO_Central.
DR GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:0045022; P:early endosome to late endosome transport; IBA:GO_Central.
DR GO; GO:0008333; P:endosome to lysosome transport; IBA:GO_Central.
DR GO; GO:0006622; P:protein targeting to lysosome; IBA:GO_Central.
DR CDD; cd07276; PX_SNX16; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR037911; SNX16_PX.
DR PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR PANTHER; PTHR22999:SF23; SORTING NEXIN-16; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PEY2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 79..193
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 198..239
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 279 AA; 32318 MW; CA6D93A85DB0EDA5 CRC64;
MASEAEVSHS PVLRTVEVER DGTSATDELT GQSLAQVGRY MYLKQDRRES LSSVSSDSGD
VSNGREHLCD VEEENVVIVP EYNTPIIGYE VMEERARFTV FKIRVEHVES GRYWFVFRRY
TDFGRLSKKL KPLFPGLQLS LPPKRWFGNN FDPMFLEDRL LGLQAFVKNI MGHRDISKSS
PVREFFCLDD PPEPLDTIEE SRALCENLEE KVYRLSQQLQ ERDTEIEVLR AELESLRLQQ
GVLVKALKWV APISCFFGWL MTEEFLLRQT LAERQGKKD
//
