ID B7PFM1_IXOSC Unreviewed; 230 AA.
AC B7PFM1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Peroxisomal N1-acetyl-spermine/spermidine oxidase, putative {ECO:0000313|EMBL:EEC05393.1, ECO:0000313|EnsemblMetazoa:ISCW005122-PA};
DE EC=1.5.3.11 {ECO:0000313|EMBL:EEC05393.1};
GN ORFNames=IscW_ISCW005122 {ECO:0000313|EMBL:EEC05393.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC05393.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC05393.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW005122-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW005122-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the flavin monoamine oxidase family.
CC {ECO:0000256|ARBA:ARBA00005995}.
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DR EMBL; ABJB010418798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010544656; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010709871; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS703412; EEC05393.1; -; Genomic_DNA.
DR RefSeq; XP_002433993.1; XM_002433948.1.
DR AlphaFoldDB; B7PFM1; -.
DR STRING; 6945.B7PFM1; -.
DR PaxDb; 6945-B7PFM1; -.
DR EnsemblMetazoa; ISCW005122-RA; ISCW005122-PA; ISCW005122.
DR KEGG; isc:IscW_ISCW005122; -.
DR VEuPathDB; VectorBase:ISCI005122; -.
DR VEuPathDB; VectorBase:ISCP_012039; -.
DR VEuPathDB; VectorBase:ISCW005122; -.
DR HOGENOM; CLU_067485_2_0_1; -.
DR InParanoid; B7PFM1; -.
DR OMA; MERSTWH; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.660.10; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR PANTHER; PTHR10742:SF405; PEROXISOMAL N(1)-ACETYL-SPERMINE_SPERMIDINE OXIDASE; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 1: Evidence at protein level;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EEC05393.1};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PFM1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 1..214
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 230 AA; 26112 MW; 468805C66264F128 CRC64;
MFDPPLPEKK LLAIRSLGYG TVDKVFLKYD NPFWQPTDVY QVLWLDGFNH CGNKVDQDDM
SAWVTHGQLQ TSWFRYIGRF NAVRHQPQVL CCWLSGEGAK FMETLSDDEV RTGCHQVLRQ
VLGRPDLPEP NYMERSTWHS DPFSVGSYSY IAVSCDTTGS LPLDLAEPVC EPVVHFGTEV
MYPLLLFAGE ATHSSFFSTV HGAYESGIRE ADRLADFYLD PVEGMKKRDA
//
