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Database: UniProt
Entry: B7PGF0_IXOSC
LinkDB: B7PGF0_IXOSC
Original site: B7PGF0_IXOSC 
ID   B7PGF0_IXOSC            Unreviewed;       469 AA.
AC   B7PGF0;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   30-AUG-2017, entry version 50.
DE   SubName: Full=Transporter, cation channel family protein {ECO:0000313|VectorBase:ISCW003847-PA};
GN   Name=8052514 {ECO:0000313|VectorBase:ISCW003847-PA};
GN   ORFNames=IscW_ISCW003847 {ECO:0000313|EMBL:EEC05672.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945 {ECO:0000313|Proteomes:UP000001555};
RN   [1] {ECO:0000313|EMBL:EEC05672.1, ECO:0000313|Proteomes:UP000001555, ECO:0000313|VectorBase:ISCW003847-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555,
RC   ECO:0000313|VectorBase:ISCW003847-PA}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC05672.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M.,
RA   Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J.,
RA   Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G.,
RA   Meyer J., Hill C.A., Birren B., Nene V., Collins F.,
RA   Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:ISCW003847-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|VectorBase:ISCW003847-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; ABJB010058357; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010081052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS707746; EEC05672.1; -; Genomic_DNA.
DR   RefSeq; XP_002434272.1; XM_002434227.1.
DR   STRING; 6945.ISCW003847-PA; -.
DR   EnsemblMetazoa; ISCW003847-RA; ISCW003847-PA; ISCW003847.
DR   GeneID; 8052514; -.
DR   KEGG; isc:IscW_ISCW003847; -.
DR   VectorBase; ISCW003847-RA; ISCW003847-PA; ISCW003847.
DR   CTD; 8052514; -.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   InParanoid; B7PGF0; -.
DR   OMA; CDLEREH; -.
DR   PhylomeDB; B7PGF0; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0072345; F:NAADP-sensitive calcium-release channel activity; IBA:GO_Central.
DR   GO; GO:0006816; P:calcium ion transport; IBA:GO_Central.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001555};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    110       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    251    275       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       54    281       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   469 AA;  53360 MW;  DA9F4A368BBFACF0 CRC64;
     MEECLSEPTA NEAQRRYARS LRRLISRKPV RTAPRPAGRL KGFLYDVAKS RELEFVSTLK
     VLLDGMLLAS EQHNWSYGMR RSLGKAHVIF LAGYAMELGI HAGAVGGAFL ACKWRQFELC
     TLLLSLLGSF GLPLARPLDA QWALLRGLRA LAVLKVFRSL VSVRAVRQMV LIFVASVPAF
     TNVALLLFLV MFVYAVLGVS LFSQIFPDDT DRFTVNFSRL WRALLLLFRL STSSSWNDLL
     PWLMPTGKAL AVTYIVTYVF VSNFIIFNSY VAVLLDGYEH SRNTELSGMT DSDLLEYAAG
     WARLDLEGRN LLPLASIPVL LDTLPPPLRL PLPNRLVLAI MDVPILQGDR VHYVHLLEAM
     LRVRMNMYEP LAKELDRSLE AYVATVYPEL RDPEMKPVSS TMIRQLELRA ARVLAEFFTE
     GCEQLRLEHA ARVLQRSYRA KRFRRVVDIT KRVVPFPLVI LTRTNLQYW
//
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