ID B7PMV4_IXOSC Unreviewed; 312 AA.
AC B7PMV4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Beta-arrestin, putative {ECO:0000313|EMBL:EEC07926.1, ECO:0000313|EnsemblMetazoa:ISCW006152-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW006152 {ECO:0000313|EMBL:EEC07926.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC07926.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC07926.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW006152-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW006152-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR EMBL; ABJB010858664; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010881071; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS749127; EEC07926.1; -; Genomic_DNA.
DR RefSeq; XP_002435102.1; XM_002435057.1.
DR AlphaFoldDB; B7PMV4; -.
DR STRING; 6945.B7PMV4; -.
DR PaxDb; 6945-B7PMV4; -.
DR EnsemblMetazoa; ISCW006152-RA; ISCW006152-PA; ISCW006152.
DR KEGG; isc:IscW_ISCW006152; -.
DR VEuPathDB; VectorBase:ISCI006152; -.
DR VEuPathDB; VectorBase:ISCP_032302; -.
DR VEuPathDB; VectorBase:ISCW006152; -.
DR HOGENOM; CLU_033484_0_0_1; -.
DR InParanoid; B7PMV4; -.
DR OMA; TSRHFLM; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR GO; GO:0002031; P:G protein-coupled receptor internalization; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.640; -; 1.
DR Gene3D; 2.60.40.840; -; 1.
DR InterPro; IPR000698; Arrestin.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR017864; Arrestin_CS.
DR InterPro; IPR014753; Arrestin_N.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11792; ARRESTIN; 1.
DR PANTHER; PTHR11792:SF17; KURTZ ARRESTIN; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR PRINTS; PR00309; ARRESTIN.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
DR PROSITE; PS00295; ARRESTINS; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PMV4};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 110..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 198..311
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC07926.1"
SQ SEQUENCE 312 AA; 35379 MW; F671DBFE57F985ED CRC64;
IVIPFRVFKK SSPNSKITMY LGKRDFVDHI TSVDPIDGVV LIDPDYVKDR KVFGHVLAAF
RYGREDLDVL GLTFRKDLYL ASEQIYPRLT TGENSNRPLT RLQVSSESSF FFFFLSFFYY
LFVRNLGWGG TTFPATRLPD GFCNPQRVNG HCSTAEVTQP RFCSYRNSVR LAIRKIMYAP
SRQGEQPSVE VSKEFVMSPN KLHLEASLDK ELYHHGEDIA VNVHIANNSN RTVKKVKVSV
RQFADICLFS TAQYKCTVAE IDSEEGCPVS PGFTLSKVHY LRPLLANNKD KRGLALDGQL
KHEDTNLASS TM
//
