ID B7PN84_IXOSC Unreviewed; 189 AA.
AC B7PN84;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=L-serine ammonia-lyase {ECO:0000256|ARBA:ARBA00012093};
DE EC=4.3.1.17 {ECO:0000256|ARBA:ARBA00012093};
DE AltName: Full=L-serine deaminase {ECO:0000256|ARBA:ARBA00041766};
DE AltName: Full=L-threonine dehydratase {ECO:0000256|ARBA:ARBA00042605};
GN ORFNames=IscW_ISCW005673 {ECO:0000313|EMBL:EEC08056.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC08056.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC08056.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW005673-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW005673-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABJB010290623; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010597602; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010617323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010847856; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010857410; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010932694; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010943258; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011038830; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011083956; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS751205; EEC08056.1; -; Genomic_DNA.
DR RefSeq; XP_002435232.1; XM_002435187.1.
DR AlphaFoldDB; B7PN84; -.
DR STRING; 6945.B7PN84; -.
DR PaxDb; 6945-B7PN84; -.
DR EnsemblMetazoa; ISCW005673-RA; ISCW005673-PA; ISCW005673.
DR KEGG; isc:IscW_ISCW005673; -.
DR VEuPathDB; VectorBase:ISCI005673; -.
DR VEuPathDB; VectorBase:ISCP_025120; -.
DR VEuPathDB; VectorBase:ISCW005673; -.
DR HOGENOM; CLU_021152_3_2_1; -.
DR InParanoid; B7PN84; -.
DR OMA; WNTANEM; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0003941; F:L-serine ammonia-lyase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1100; -; 1.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR48078:SF2; CATABOLIC L-SERINE_THREONINE DEHYDRATASE; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:EEC08056.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 3..157
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 189 AA; 19843 MW; D8DB3F01324F1C2A CRC64;
MIPEIFEDLC GVAPGAIVAS VGGGGLVCGI AEGLDKVGWS QVPIVAVETK GADSFRASIN
ANKQVTLPTI TSIAAALAVR KVCTKILELY KTRPIFSVVL SDKLAVDACV RFSEDQRALV
EPACGASLAA VYGARTTEMR KHGRLPADKP IVVIVCGGSA ASIKQLEEWQ EAVQRNGCPS
PERDHTGID
//
