ID B7PNY7_IXOSC Unreviewed; 281 AA.
AC B7PNY7;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE SubName: Full=DNAation factor, putative {ECO:0000313|EMBL:EEC08309.1};
DE Flags: Fragment;
GN Name=8051182 {ECO:0000313|EnsemblMetazoa:ISCW018943-PA};
GN ORFNames=IscW_ISCW018943 {ECO:0000313|EMBL:EEC08309.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC08309.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC08309.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW018943-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW018943-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010254573; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010828335; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS755062; EEC08309.1; -; Genomic_DNA.
DR RefSeq; XP_002435479.1; XM_002435434.1.
DR AlphaFoldDB; B7PNY7; -.
DR STRING; 6945.B7PNY7; -.
DR PaxDb; 6945-B7PNY7; -.
DR EnsemblMetazoa; ISCW018943-RA; ISCW018943-PA; ISCW018943.
DR GeneID; 8051182; -.
DR KEGG; isc:IscW_ISCW018943; -.
DR VEuPathDB; VectorBase:ISCI018943; -.
DR VEuPathDB; VectorBase:ISCP_012189; -.
DR VEuPathDB; VectorBase:ISCW018943; -.
DR HOGENOM; CLU_049235_1_0_1; -.
DR InParanoid; B7PNY7; -.
DR OMA; KEALCCE; -.
DR OrthoDB; 5399497at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004520; F:DNA endonuclease activity; IEA:InterPro.
DR GO; GO:0004536; F:DNA nuclease activity; IBA:GO_Central.
DR GO; GO:0006309; P:apoptotic DNA fragmentation; IBA:GO_Central.
DR InterPro; IPR039729; DFF40.
DR InterPro; IPR015311; DFF40_C.
DR InterPro; IPR044925; His-Me_finger_sf.
DR PANTHER; PTHR13067; CASPASE-ACTIVATED DNASE; 1.
DR PANTHER; PTHR13067:SF2; CASPASE-ACTIVATED DNASE; 1.
DR Pfam; PF09230; DFF40; 1.
DR SUPFAM; SSF54060; His-Me finger endonucleases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 58..276
FT /note="DNA fragmentation factor 40 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09230"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC08309.1"
FT NON_TER 281
FT /evidence="ECO:0000313|EMBL:EEC08309.1"
SQ SEQUENCE 281 AA; 32261 MW; 3B5151C5361E858D CRC64;
LEDGTEIDDE YLATCGDYTV FSVLRPSETI KYIPQKAKEL VGHFTRLLAS RSNEVVAALE
PYKSQLIEQM LGNIESLEVP EHVLLADNKD QDPKWFEGEK RATSKRKVMR ERAKTRIKGY
FYKSKEDLQK CVSENGKQCL SQLFEEFSAL LRAGDHNGHY FVRGEKEALC CEKGQFLCQG
TFSKPSCDSR VHRINPYGSR EQLVCFSTWN LDHRVERSRS ILPAIGKAIE EANGRILNAR
YFYKLLFTTD NLKLVHPVCH IKSEHGGFKC ERAHWYVDDG A
//
