ID B7PQP3_IXOSC Unreviewed; 606 AA.
AC B7PQP3;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE SubName: Full=T-cell immunomodulatory protein, putative {ECO:0000313|EMBL:EEC08915.1, ECO:0000313|EnsemblMetazoa:ISCW006297-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW006297 {ECO:0000313|EMBL:EEC08915.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC08915.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC08915.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW006297-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW006297-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TIP family. {ECO:0000256|ARBA:ARBA00006496}.
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DR EMBL; ABJB010756857; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010778317; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS766552; EEC08915.1; -; Genomic_DNA.
DR RefSeq; XP_002436085.1; XM_002436040.1.
DR AlphaFoldDB; B7PQP3; -.
DR STRING; 6945.B7PQP3; -.
DR PaxDb; 6945-B7PQP3; -.
DR EnsemblMetazoa; ISCW006297-RA; ISCW006297-PA; ISCW006297.
DR KEGG; isc:IscW_ISCW006297; -.
DR VEuPathDB; VectorBase:ISCI006297; -.
DR VEuPathDB; VectorBase:ISCP_011283; -.
DR VEuPathDB; VectorBase:ISCP_021447; -.
DR VEuPathDB; VectorBase:ISCW006297; -.
DR HOGENOM; CLU_020272_2_0_1; -.
DR InParanoid; B7PQP3; -.
DR OMA; PGDWIPW; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR024881; Tip.
DR PANTHER; PTHR13412:SF0; T-CELL IMMUNOMODULATORY PROTEIN; 1.
DR PANTHER; PTHR13412; T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG; 1.
DR Pfam; PF13517; FG-GAP_3; 2.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PQP3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..606
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010959779"
FT TRANSMEM 561..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC08915.1"
SQ SEQUENCE 606 AA; 67027 MW; 4321988ABBAC586A CRC64;
LQRFIQNPRR AVMNRRLLVV TVVATIVQRV CSFRDITDSV FGSANTGVLA AFGDFNSDKL
TDLFLISSDM HNLDIRIATG AKPTFQKSDV KCTVPGIITS VMPGDFDGDS IMDILVTAKA
DPSSKDLKIH IFWGQLSLGI DCGNGTTLVA TDQPLLFDHN SDRVVDLLSG KPGDDPRTRT
VWTFGASRSP TTHALGIGFG KLASPHSNSF VDLNDDMTAD LMLTAESAME LWHWTGDGTF
SGPKRRDYPS NAAVKGQSLF VDIDADGDME HVMPVCLGQS DCRNSSIVVF NSSGWITWLD
GFHDASNQVW RFFRDAEGTR LAVPTALRTA DVDMDGYPDF LAVLEGRPKD RKGPVRRATL
LLNVRCPSCP FGRKLVPYWN YGALATFDSV RLAAFFDIDE DGQMDVLLTN GTKEDGLRTH
ALRNQFSDDA CFIKVLAVSG LCYANCPLGQ IAYGTNQPGP FVRYRIITNK TNLAESCTSQ
LYQSAHFSLQ LPYTVFGLGQ SPNFVDVLTV AFPNNASTKH PSVHHQWTQI IPNSQMVIIP
HPPDQPSQWI NKLFVTPGRQ VLLTFIALAG TCVFISLIIA AFHWLEKRED RRVKLQEAHQ
FHFDAM
//
