GenomeNet

Database: UniProt
Entry: B7PRF3_IXOSC
LinkDB: B7PRF3_IXOSC
Original site: B7PRF3_IXOSC 
ID   B7PRF3_IXOSC            Unreviewed;       476 AA.
AC   B7PRF3;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   25-OCT-2017, entry version 54.
DE   SubName: Full=Ryanodine receptor, putative {ECO:0000313|EMBL:EEC09175.1};
DE   SubName: Full=Ryanodine receptor, putative (Fragment) {ECO:0000313|VectorBase:ISCW007202-PA};
DE   Flags: Fragment;
GN   Name=8030261 {ECO:0000313|VectorBase:ISCW007202-PA};
GN   ORFNames=IscW_ISCW007202 {ECO:0000313|EMBL:EEC09175.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945 {ECO:0000313|Proteomes:UP000001555};
RN   [1] {ECO:0000313|EMBL:EEC09175.1, ECO:0000313|Proteomes:UP000001555, ECO:0000313|VectorBase:ISCW007202-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555,
RC   ECO:0000313|VectorBase:ISCW007202-PA}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC09175.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M.,
RA   Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J.,
RA   Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G.,
RA   Meyer J., Hill C.A., Birren B., Nene V., Collins F.,
RA   Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:ISCW007202-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|VectorBase:ISCW007202-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; ABJB010186763; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010439823; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010576682; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010771607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS772334; EEC09175.1; -; Genomic_DNA.
DR   RefSeq; XP_002399595.1; XM_002399553.1.
DR   UniGene; Isc.7898; -.
DR   STRING; 6945.ISCW007202-PA; -.
DR   EnsemblMetazoa; ISCW007202-RA; ISCW007202-PA; ISCW007202.
DR   GeneID; 8030261; -.
DR   KEGG; isc:IscW_ISCW007202; -.
DR   VectorBase; ISCW007202-RA; ISCW007202-PA; ISCW007202.
DR   CTD; 8030261; -.
DR   eggNOG; KOG2243; Eukaryota.
DR   eggNOG; ENOG410YCNW; LUCA.
DR   InParanoid; B7PRF3; -.
DR   OMA; KEMSAPE; -.
DR   OrthoDB; EOG091G02NI; -.
DR   PhylomeDB; B7PRF3; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR033215; RyR1.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   PANTHER; PTHR13715:SF15; PTHR13715:SF15; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001555};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:EEC09175.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     55     73       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    138    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    281    304       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    325    347       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    401    424       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    163       RR_TM4-6. {ECO:0000259|Pfam:PF06459}.
FT   DOMAIN      286    433       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EEC09175.1}.
SQ   SEQUENCE   476 AA;  54104 MW;  CE0780B7AC68D03B CRC64;
     ALPGPEAMPP SPLLMPPMAS PEAAKPSETP PVAAIDLSEY SQKIVSFLAR NFYNMKYIAL
     VLAFFINFIL LFYKVNADAG SGSDDEAEPA STVGNGLADL LSNATEAVAS GSDSEDEDLE
     EWVIIEEKFF YLEPVIRFMA LFHSLVSFCM LIAYYHLKVP LAIFKREKEV ARAMEFDGLY
     ISEEPAEDDI RTRWDKLVIS TKSFPVNYWD KFVKKRVRQK YSETYDPEAL SNVLGMDKSG
     SFSQEQEESG GLIPFITNAD WKYQIWKSGV TITDNSFLYN LWYFLFSVMG NLNYFFFAAH
     LLDVAVGFKT LRTILQSVTH NGKQLVLTVM LLTIIVYIYT VIAFSFFRKF YIQEEDDQID
     PKCHSMLSCF VFHLYKGVRA GGGIGDEIGP PDGDDYEVYR IIFDITFFFF VIVILLAIIQ
     GLIIDAFGEL RDQLQSVVDD MESNCFICGI GKDYFDRVPH GFDTHVQKEH NLANYM
//
DBGET integrated database retrieval system