ID B7PVI9_IXOSC Unreviewed; 786 AA.
AC B7PVI9;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=CUB domain-containing protein {ECO:0000259|PROSITE:PS01180};
GN ORFNames=IscW_ISCW007148 {ECO:0000313|EMBL:EEC10611.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC10611.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC10611.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW007148-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW007148-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; ABJB010037792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010040435; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010133822; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010240300; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010781940; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010898336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS800078; EEC10611.1; -; Genomic_DNA.
DR RefSeq; XP_002408072.1; XM_002408028.1.
DR AlphaFoldDB; B7PVI9; -.
DR STRING; 6945.B7PVI9; -.
DR PaxDb; 6945-B7PVI9; -.
DR EnsemblMetazoa; ISCW007148-RA; ISCW007148-PA; ISCW007148.
DR KEGG; isc:IscW_ISCW007148; -.
DR VEuPathDB; VectorBase:ISCI007148; -.
DR VEuPathDB; VectorBase:ISCP_001191; -.
DR VEuPathDB; VectorBase:ISCP_025377; -.
DR VEuPathDB; VectorBase:ISCP_029739; -.
DR VEuPathDB; VectorBase:ISCW007148; -.
DR HOGENOM; CLU_356905_0_0_1; -.
DR InParanoid; B7PVI9; -.
DR OMA; GFPESYP; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IBA:GO_Central.
DR CDD; cd00041; CUB; 6.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 6.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24255; COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED; 1.
DR PANTHER; PTHR24255:SF31; CUB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00431; CUB; 6.
DR SMART; SM00042; CUB; 6.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 6.
DR PROSITE; PS01180; CUB; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00059}; Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..786
FT /note="CUB domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010826420"
FT DOMAIN 52..123
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 181..291
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 305..412
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 425..536
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 537..661
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 675..784
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 142..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 675..702
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
SQ SEQUENCE 786 AA; 88308 MW; 0AB62DACC72120A5 CRC64;
MERTSSFVAV PMVFLTWLLA SSVPGALAQN RSSADQVLSA PVYARTSDVC TLRLTFNDFE
LEDSPDCFND YLLLPDGQKI CGTLPPDTTK TVSISRRHSS FTFLFSSNEA KTGKGFMVKI
VQEPYTCSDD LPDSSLFPTD SLPEDFGPTA ARPQDFDPPV ARPQEFNPVT RPQAQTGSSR
CDQEILGYSH VLSSPGYPVG YPPNQRCSYR VWRADRSVCV VELDVQDFSL NDRRQYCSRD
YLDLPDGTRF CGKVTGTKLL EFAPGSESFT MTFVSDFFGS GRGFNVYVRQ RPHSCGRSPF
GPRGCDQRLL GPSGLIRSPG YPRIYGPNMR CRYTLLRLNS GVCRVQISFK RFNLENSYGC
RKDYLELPDR SRLCGRYTGT RTYDFKQDFL NLYFISDRFR ADSGFEIEVR QLQNSCLNPS
AQRGCDRTVS RDIEIIRSPE YPSDYPPGSY CVYTVRRSRP GICQVRLDMI DFDVEDGLDC
TADSLTFENN GERLCGFRSG SSKVLPFPRE ADELRMVFTS DITTNRKGFE IKVTQEAGGC
FRAPLTDPGH VRAPALQFGR TGEPRHPFAY PPNLDCHYWI HRASPSVCRA QLRFSRFDVG
SPLGGVCASD YLDIQGTRYC GRRDGQTLIV DFPEGKNSLE LILHSDSVSE KSGFHLDVTQ
LSSGCIRPPL PAQSCDQTVR RESFQLMSPG FRQGGYPPST HCVYTVKKHD FRVCALEVKM
EAFDLEQDSG CSKDYLQFNN LRFCGKQAYG TTRTIEFLDD EMKVQFHANP TVSGAGFLLS
GKQVIC
//
