ID   B7PVK8_IXOSC            Unreviewed;       132 AA.
AC   B7PVK8;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=Fatty acid synthase {ECO:0000256|ARBA:ARBA00018769};
DE            EC=2.3.1.85 {ECO:0000256|ARBA:ARBA00012873};
DE   Flags: Fragment;
GN   ORFNames=IscW_ISCW008122 {ECO:0000313|EMBL:EEC10630.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945;
RN   [1] {ECO:0000313|EMBL:EEC10630.1, ECO:0000313|Proteomes:UP000001555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC10630.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA   Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA   Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA   Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ISCW008122-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW008122-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ABJB010484561; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS800288; EEC10630.1; -; Genomic_DNA.
DR   RefSeq; XP_002408143.1; XM_002408099.1.
DR   AlphaFoldDB; B7PVK8; -.
DR   STRING; 6945.B7PVK8; -.
DR   PaxDb; 6945-B7PVK8; -.
DR   EnsemblMetazoa; ISCW008122-RA; ISCW008122-PA; ISCW008122.
DR   KEGG; isc:IscW_ISCW008122; -.
DR   VEuPathDB; VectorBase:ISCI011310; -.
DR   VEuPathDB; VectorBase:ISCW008122; -.
DR   HOGENOM; CLU_1922302_0_0_1; -.
DR   InParanoid; B7PVK8; -.
DR   OMA; TIGMEVF; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0004312; F:fatty acid synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd05195; enoyl_red; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR43775:SF7; FATTY ACID SYNTHASE; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000313|EMBL:EEC10630.1};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW   Transferase {ECO:0000313|EMBL:EEC10630.1}.
FT   DOMAIN          1..117
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEC10630.1"
FT   NON_TER         132
FT                   /evidence="ECO:0000313|EMBL:EEC10630.1"
SQ   SEQUENCE   132 AA;  14576 MW;  63CC3A26D128D07B CRC64;
     VDLVLNSLAE EKLQASVRCL ATHGRFLEIG KFDLSQNNAL GMAVFLKNVS FQGIMLDALF
     GDDPRVVADK RRVIQLVREG IASGAVRPLD AVRFARDRAE EAFRFMASGK HMGKVVLEVG
     VPRRSPDRPD RG
//