ID B7Q2B0_IXOSC Unreviewed; 225 AA.
AC B7Q2B0;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=glutathione transferase {ECO:0000256|ARBA:ARBA00012452};
DE EC=2.5.1.18 {ECO:0000256|ARBA:ARBA00012452};
GN ORFNames=IscW_ISCW008578 {ECO:0000313|EMBL:EEC12982.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC12982.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC12982.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW008578-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW008578-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010280070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010356135; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010371466; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010821486; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS842862; EEC12982.1; -; Genomic_DNA.
DR RefSeq; XP_002410641.1; XM_002410596.1.
DR AlphaFoldDB; B7Q2B0; -.
DR STRING; 6945.B7Q2B0; -.
DR PaxDb; 6945-B7Q2B0; -.
DR EnsemblMetazoa; ISCW008578-RA; ISCW008578-PA; ISCW008578.
DR KEGG; isc:IscW_ISCW008578; -.
DR VEuPathDB; VectorBase:ISCI013757; -.
DR VEuPathDB; VectorBase:ISCP_035600; -.
DR VEuPathDB; VectorBase:ISCW008578; -.
DR HOGENOM; CLU_039475_2_0_1; -.
DR InParanoid; B7Q2B0; -.
DR OMA; NNELEPW; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR11571; GLUTATHIONE S-TRANSFERASE; 1.
DR PANTHER; PTHR11571:SF222; GLUTATHIONE S-TRANSFERASE 2-RELATED; 1.
DR Pfam; PF14497; GST_C_3; 1.
DR Pfam; PF02798; GST_N; 1.
DR SFLD; SFLDG01205; AMPS.1; 1.
DR SFLD; SFLDG00363; AMPS_(cytGST):_Alpha-__Mu-__Pi; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000313|EMBL:EEC12982.1}.
FT DOMAIN 1..89
FT /note="GST N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50404"
FT DOMAIN 91..209
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
SQ SEQUENCE 225 AA; 26751 MW; 9AE421EAA6A73D29 CRC64;
MAPVLGYWDT RGRAQMIRNL LIYKNNVAFV DKRYSYGPPP YYTGTEWEAD KFSLGLKFPN
LPYYIDGDLK LTQSLAIMRY LSRKHDLAGR TEEEVTQLDL LEQQSLDLFM KLARTAFEPN
LEEARKNYEA SLNNELEPWA ELLHGRTWAL GGRLTYVDFI LYESLDWIRD FGPDTFQRFS
TLLKYLNKFE ELPNIKQYMA SQKYRKYPFL RRKWTWAAKE TSSQF
//
