ID B7Q4R1_IXOSC Unreviewed; 549 AA.
AC B7Q4R1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Potassium channel, putative {ECO:0000313|EMBL:EEC13833.1, ECO:0000313|EnsemblMetazoa:ISCW021761-PA};
GN ORFNames=IscW_ISCW021761 {ECO:0000313|EMBL:EEC13833.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC13833.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC13833.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW021761-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW021761-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ABJB010414429; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS857340; EEC13833.1; -; Genomic_DNA.
DR RefSeq; XP_002411599.1; XM_002411554.1.
DR AlphaFoldDB; B7Q4R1; -.
DR STRING; 6945.B7Q4R1; -.
DR PaxDb; 6945-B7Q4R1; -.
DR EnsemblMetazoa; ISCW021761-RA; ISCW021761-PA; ISCW021761.
DR KEGG; isc:IscW_ISCW021761; -.
DR VEuPathDB; VectorBase:ISCI021761; -.
DR VEuPathDB; VectorBase:ISCP_014593; -.
DR VEuPathDB; VectorBase:ISCW021761; -.
DR HOGENOM; CLU_011722_4_0_1; -.
DR InParanoid; B7Q4R1; -.
DR OMA; INHSAFK; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IBA:GO_Central.
DR GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:GO_Central.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF254; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01496; SHAKERCHANEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000313|EMBL:EEC13833.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 222..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..191
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
SQ SEQUENCE 549 AA; 61198 MW; A3AC27E2840D7FAF CRC64;
MSLGFALCEL RVPNWHVLGV AVLFPDSERC STGVLSRDVL CRRSLPKLSS EDATGGCEAA
LSGAGLVSPS GGAGGGGGNF EPIPHEHDLC ERVVINVSGL RFETQLRTLH QFPDTLLGDP
GRRLRYFDPL RNEYFFDRNR PSFDAILYYY QSGGRLRRPV NVPLDVFAEE IKFYELGEGT
FNKFREDEGF IKEEERPLPG RDLQRRVWLL FEYPESSQAA RVVAIVSVVV ILLSIVIFCL
ETLPEFKHYR MYPAGNNMTR VVEDEVPKLT EPFFLIETCC IVWFTFELFV RFCACPCKIA
FFKDVMNSID LVAIIPYFIT LGTVIARERE GPGFLPPDKS SNQAMSLAIL RVIRLVRVFR
IFKLSRHSKG LQILGRTLRA SMRELGLLIF FLFIGVILFS SAVYYAEADS DRSYFKSIPD
AFWWAVVTMT TVGYGDMRPV GVWGKIVGSL CAIAGVLTIA LPVPVIVSNF NYFYHRETDQ
EEMQSQSFNH VTSCPYLPGT VVAAKLKGDS DSADSDVLEL DDDAVAAAAL FANPAPGQAN
GAASLETDV
//
