ID B7Q6G8_IXOSC Unreviewed; 316 AA.
AC B7Q6G8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE SubName: Full=GTP-binding protein, putative {ECO:0000313|EMBL:EEC14440.1, ECO:0000313|EnsemblMetazoa:ISCW011735-PA};
GN Name=8036605 {ECO:0000313|EnsemblMetazoa:ISCW011735-PA};
GN ORFNames=IscW_ISCW011735 {ECO:0000313|EMBL:EEC14440.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC14440.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC14440.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW011735-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW011735-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GTR/RAG GTP-binding protein family.
CC {ECO:0000256|ARBA:ARBA00007756, ECO:0000256|RuleBase:RU367014}.
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DR EMBL; ABJB010868359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS867564; EEC14440.1; -; Genomic_DNA.
DR RefSeq; XP_002411961.1; XM_002411916.1.
DR AlphaFoldDB; B7Q6G8; -.
DR STRING; 6945.B7Q6G8; -.
DR PaxDb; 6945-B7Q6G8; -.
DR EnsemblMetazoa; ISCW011735-RA; ISCW011735-PA; ISCW011735.
DR GeneID; 8036605; -.
DR KEGG; isc:IscW_ISCW011735; -.
DR VEuPathDB; VectorBase:ISCI011735; -.
DR VEuPathDB; VectorBase:ISCP_007544; -.
DR VEuPathDB; VectorBase:ISCW011735; -.
DR HOGENOM; CLU_044099_1_0_1; -.
DR InParanoid; B7Q6G8; -.
DR OMA; LIPNMQD; -.
DR OrthoDB; 33171at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:1990131; C:Gtr1-Gtr2 GTPase complex; IBA:GO_Central.
DR GO; GO:0005764; C:lysosome; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0009267; P:cellular response to starvation; IBA:GO_Central.
DR GO; GO:0010507; P:negative regulation of autophagy; IBA:GO_Central.
DR CDD; cd11384; RagA_like; 1.
DR Gene3D; 3.30.450.190; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006762; Gtr1_RagA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039397; RagA/B.
DR PANTHER; PTHR11259; RAS-RELATED GTP BINDING RAG/GTR YEAST; 1.
DR PANTHER; PTHR11259:SF1; RAS-RELATED GTP-BINDING PROTEIN; 1.
DR Pfam; PF04670; Gtr1_RagA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 1: Evidence at protein level;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU367014};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU367014};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7Q6G8};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
SQ SEQUENCE 316 AA; 36488 MW; 04AD738BE2E238DB CRC64;
MQNRSSAMKK KVLLMGKSGS GKTSMRSIIF ANYIARDTRR LGATIDVEHS HVRFLGNLVL
NLWDCGGQEA FMENYFASQK DTIFRNVEVL IYVFDVESRE LEKDLHYYQS CLEAILQNSA
EAKIFCLVHK MDLVPEEERE RIFQLRQEDL NKLSKPLECT CFKTSIWDET LYKAWSSIVY
TLVPNVQQLE TNLQQFTNII DANEVLLFEK ATFLIISHCQ RKQHHDVHRF EKVSNIIKQF
KLSCSKLAAQ FHSMEVRNGN FAAFIDAFTP NTYIMVIMAD PSMPSAATLI NIKNARKHFE
KLEGAKSPNS QSLVRR
//
