ID B7Q6M6_IXOSC Unreviewed; 309 AA.
AC B7Q6M6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Salivary sulfotransferase, putative {ECO:0000313|EMBL:EEC14498.1, ECO:0000313|EnsemblMetazoa:ISCW010543-PA};
DE EC=2.8.2.2 {ECO:0000313|EMBL:EEC14498.1};
GN Name=8036673 {ECO:0000313|EnsemblMetazoa:ISCW010543-PA};
GN ORFNames=IscW_ISCW010543 {ECO:0000313|EMBL:EEC14498.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC14498.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC14498.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW010543-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW010543-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771}.
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DR EMBL; ABJB010183536; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS868927; EEC14498.1; -; Genomic_DNA.
DR RefSeq; XP_002403168.1; XM_002403124.1.
DR AlphaFoldDB; B7Q6M6; -.
DR PaxDb; 6945-B7Q6M6; -.
DR EnsemblMetazoa; ISCW010543-RA; ISCW010543-PA; ISCW010543.
DR KEGG; isc:IscW_ISCW010543; -.
DR VEuPathDB; VectorBase:ISCI010543; -.
DR VEuPathDB; VectorBase:ISCP_015818; -.
DR VEuPathDB; VectorBase:ISCW010543; -.
DR HOGENOM; CLU_027239_2_0_1; -.
DR InParanoid; B7Q6M6; -.
DR OMA; WHELFSP; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004027; F:alcohol sulfotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF334; SULFOTRANSFERASE SSU-1; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EEC14498.1}.
FT DOMAIN 37..299
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 309 AA; 36044 MW; 258481D93666218E CRC64;
MEHKRRAPLI QLIDGIKRSP FLKPSVVREA LKYRPRDGDI VLVTYAKGGS HWTQRIIQLL
LDREDVPSTY SDFVRRTPVL EYHGAAAVND MPPPRFFRTH LQLLRNNFND KAKYVYVARN
PWDTCVSLYH YTRRLPKHQF EDGTFDDFFE AFVTGELGFG EYFDHVLHGY ARKDDPNVFF
MTYEELKADA PGMVLKLAYF LGEEYGNMLE GSEEIFQGVL MKSSFEFMSR VLQPREEEFS
AAFENSFSLV DKLSSSGPEG SKDNDFRLFR KGKVNDWHEL FSPDQIQRMQ ARIDKMTEGT
DIMSLWNVK
//
