ID B7QAW8_IXOSC Unreviewed; 418 AA.
AC B7QAW8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Zinc finger protein, putative {ECO:0000313|EMBL:EEC15990.1, ECO:0000313|EnsemblMetazoa:ISCW012059-PA};
GN ORFNames=IscW_ISCW012059 {ECO:0000313|EMBL:EEC15990.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC15990.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC15990.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW012059-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW012059-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABJB010128423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010363789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010657024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010800261; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010805554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010833887; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS897019; EEC15990.1; -; Genomic_DNA.
DR RefSeq; XP_002412694.1; XM_002412649.1.
DR AlphaFoldDB; B7QAW8; -.
DR STRING; 6945.B7QAW8; -.
DR PaxDb; 6945-B7QAW8; -.
DR EnsemblMetazoa; ISCW012059-RA; ISCW012059-PA; ISCW012059.
DR KEGG; isc:IscW_ISCW012059; -.
DR VEuPathDB; VectorBase:ISCI012059; -.
DR VEuPathDB; VectorBase:ISCP_029672; -.
DR VEuPathDB; VectorBase:ISCW012059; -.
DR HOGENOM; CLU_031462_2_0_1; -.
DR InParanoid; B7QAW8; -.
DR OMA; REAIYHC; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0035064; F:methylated histone binding; IBA:GO_Central.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0009966; P:regulation of signal transduction; IBA:GO_Central.
DR GO; GO:0034243; P:regulation of transcription elongation by RNA polymerase II; IBA:GO_Central.
DR CDD; cd20159; PWWP_BS69; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047268; PWWP_BS69.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR047269; ZMY11.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR002893; Znf_MYND.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46379; ZINC FINGER MYND DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR46379:SF1; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 58..103
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 138..189
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 379..414
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 214..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 299..372
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 232..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 48467 MW; 3A72C587274064BE CRC64;
MRRKHHLSAA DTERQLGHAV RDALMLSRKK MGFKGSKVGV PQEAFQLPEE PPERDGHDWY
CFECHRGGDV LLCTSCHRVY HVVCVKEDLS NEEKFVCSVC QLLQEKDELK LKAEDLNMLL
GYTCVRLKDK TCTPCDPPHD LVFAKQKGFP YWPAKVIRID DHCYDVRFFG GYHQRALVDR
SNIKPIGTSL KQIAAKRTTA LNKALEELKR HQQLLEHRSR GTSGDCSSPA RHSPVKAKRL
DESSSEDHNV VSSSCQESPS CRVSTSTQTH KKMLVSKAAG EEARCDCEAR HQLSSKDLRE
ELEAKHARDR ERLAQEIEEK VRKQCEAEKL KEVGSVLERM REELEQHKLR DRDAHEQELA
ALEERHRQEI SDTKKKQWCY NCEAEAIYHC CWNTLYCSVE CQQVHWHKEH KRSCRRKQ
//
