ID B7QBS1_IXOSC Unreviewed; 252 AA.
AC B7QBS1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Bardet-Biedl syndrome 4, putative {ECO:0000313|EMBL:EEC16293.1, ECO:0000313|EnsemblMetazoa:ISCW012602-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW012602 {ECO:0000313|EMBL:EEC16293.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC16293.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC16293.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW012602-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW012602-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000256|ARBA:ARBA00004309}.
CC -!- SIMILARITY: Belongs to the BBS4 family.
CC {ECO:0000256|ARBA:ARBA00023778}.
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DR EMBL; ABJB010134134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010479264; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010515011; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010706155; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010736709; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS903228; EEC16293.1; -; Genomic_DNA.
DR RefSeq; XP_002412985.1; XM_002412940.1.
DR AlphaFoldDB; B7QBS1; -.
DR STRING; 6945.B7QBS1; -.
DR PaxDb; 6945-B7QBS1; -.
DR EnsemblMetazoa; ISCW012602-RA; ISCW012602-PA; ISCW012602.
DR KEGG; isc:IscW_ISCW012602; -.
DR VEuPathDB; VectorBase:ISCP_028088; -.
DR VEuPathDB; VectorBase:ISCW012602; -.
DR HOGENOM; CLU_1105013_0_0_1; -.
DR InParanoid; B7QBS1; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44186; -; 1.
DR PANTHER; PTHR44186:SF1; BARDET-BIEDL SYNDROME 4 PROTEIN; 1.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 117..150
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 24..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC16293.1"
FT NON_TER 252
FT /evidence="ECO:0000313|EMBL:EEC16293.1"
SQ SEQUENCE 252 AA; 27688 MW; D65C50382DBEE19A CRC64;
AAAVPESVLL SDRPLERETV YKTPPLPGIH AEGRTMSNPD KSQRCSHGLR PGQCQGRRWR
AQRAASLVLG HGRRNTGKSV EIPNDICHYL GVCYVKLNNY EKAKEHLYEA LQQSPRDETF
IELGELHVRT GDIKSAMSVY RKAVDNHPGS AELNTKLGLL YIQAGAKCTR PEDHGLVQGN
MYQKAFERLG AALAVDSSYA PAVLAAGSIM QTYGDFEVAL SKYRAIAAAL PDSPALWNNI
GMCFFGKKKY VA
//
