ID B7QMG3_IXOSC Unreviewed; 613 AA.
AC B7QMG3;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Irregular chiasm C-roughest protein, putative {ECO:0000313|EMBL:EEC20035.1, ECO:0000313|EnsemblMetazoa:ISCW023039-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW023039 {ECO:0000313|EMBL:EEC20035.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC20035.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC20035.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW023039-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW023039-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; ABJB010179297; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010310037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010349834; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010499866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010806974; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS971334; EEC20035.1; -; Genomic_DNA.
DR RefSeq; XP_002416368.1; XM_002416323.1.
DR AlphaFoldDB; B7QMG3; -.
DR STRING; 6945.B7QMG3; -.
DR PaxDb; 6945-B7QMG3; -.
DR EnsemblMetazoa; ISCW023039-RA; ISCW023039-PA; ISCW023039.
DR KEGG; isc:IscW_ISCW023039; -.
DR VEuPathDB; VectorBase:ISCI023039; -.
DR VEuPathDB; VectorBase:ISCP_011941; -.
DR VEuPathDB; VectorBase:ISCW023039; -.
DR HOGENOM; CLU_013520_1_0_1; -.
DR InParanoid; B7QMG3; -.
DR OMA; RYEHSYG; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005911; C:cell-cell junction; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0050839; F:cell adhesion molecule binding; IBA:GO_Central.
DR GO; GO:0098609; P:cell-cell adhesion; IBA:GO_Central.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11640:SF153; IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 482..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..102
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 110..205
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 212..293
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 298..372
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 382..475
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 520..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC20035.1"
FT NON_TER 613
FT /evidence="ECO:0000313|EMBL:EEC20035.1"
SQ SEQUENCE 613 AA; 67496 MW; 4AA9D334FD9CF970 CRC64;
RPQQRFAIEP TDRSAILGDT IVLACRVINK AGTLQWTKDG FGLGSDRDLS GFPRYSMVGS
DDEGDFSLQI GSVSLEDDAT FQCQVGAVDG VKGIRSRSAP LTVFVPPEPP KIVQGEFLKT
TAGMTVELTC ESHAGKPPAE LTWLDGSGNV VSSGVEYKTE LLSDGKRANA ALTWTLSPSR
EHDGKTFVCR SENKALKQPM LATIRMEEKY PPDITLTVES DKISEFDDVR FHCQAVANPS
DIVYKWYRND EIIAGDHTTE LVLPRVTRNF NGDTITCEAR NDVGTTKSTH TLNIHYRPAF
KKPEETVAAE EGTEVTLHCE VDSNPKPDIV WHHEGSEHVL GKQATLVIPA MRSHDAGRYS
CRATVPGFPE ITQDVHVYVK GPPKVKSPTT QYGVEGEEVR VECVVTSVPP PTRVAWSRNT
QLVDIDNNQG YEIIKEPLSN GLRNLLIIHN AEEDDFGQYN CSVWNPFGYD TRLITVRKQK
NLPMLIILAG VIGGIVLVVT VTISIILCLR KKNIVKDDDF NSEKKGKQSD SASSGDSDIK
ESQNNNGYIP YVDYARDYNP PAPSLQLNAS RDSGLYGSSP QSLNDLGQGI DPRFRAGYAN
PYLRTSQSTL PPP
//
