ID B7QN25_IXOSC Unreviewed; 223 AA.
AC B7QN25;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Guanylate cyclase C, putative {ECO:0000313|EMBL:EEC20247.1};
DE EC=4.6.1.2 {ECO:0000313|EMBL:EEC20247.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW023978 {ECO:0000313|EMBL:EEC20247.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC20247.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel colony {ECO:0000313|EMBL:EEC20247.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-4/guanylyl cyclase
CC family. {ECO:0000256|RuleBase:RU000405}.
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DR EMBL; DS975458; EEC20247.1; -; Genomic_DNA.
DR RefSeq; XP_002400586.1; XM_002400542.1.
DR AlphaFoldDB; B7QN25; -.
DR STRING; 6945.B7QN25; -.
DR PaxDb; 6945-B7QN25; -.
DR KEGG; isc:IscW_ISCW023978; -.
DR VEuPathDB; VectorBase:ISCI023978; -.
DR VEuPathDB; VectorBase:ISCP_036198; -.
DR VEuPathDB; VectorBase:ISCW023978; -.
DR OMA; QGKGKMY; -.
DR PhylomeDB; B7QN25; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004383; F:guanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR018297; A/G_cyclase_CS.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR11920:SF494; GUANYLATE CYCLASE; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS00452; GUANYLATE_CYCLASE_1; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000405};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 28..158
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC20247.1"
FT NON_TER 223
FT /evidence="ECO:0000313|EMBL:EEC20247.1"
SQ SEQUENCE 223 AA; 24906 MW; 74FF7DFE4A55E856 CRC64;
KFGFIFRSVA SQLIKGQSVT AESYDSVTIY FSDIVGFTSL SAQSTPMQVV DLLNDLYTCF
DSIIENYDVY KVETIGDAYM VSSGLPVRNG MLHAREIARM SLALLRAVRS FSIRHRPLEQ
LKLRIGIHTG PCAAGIVGLK MPRYCLFGDT VNTASRMESN GQPLKIHVST ATKEALERFK
TFQLELRGDI ELKGKGLMTT YWLLEETPET ISPDEDGHPK ETK
//
