ID   B7R3K4_9EURY            Unreviewed;       666 AA.
AC   B7R3K4;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   RecName: Full=V-type ATP synthase subunit I {ECO:0000256|ARBA:ARBA00020764, ECO:0000256|RuleBase:RU361189};
GN   ORFNames=TAM4_1157 {ECO:0000313|EMBL:EEB73409.1};
OS   Thermococcus sp. AM4.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=246969 {ECO:0000313|EMBL:EEB73409.1, ECO:0000313|Proteomes:UP000009277};
RN   [1] {ECO:0000313|EMBL:EEB73409.1, ECO:0000313|Proteomes:UP000009277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AM4 {ECO:0000313|EMBL:EEB73409.1,
RC   ECO:0000313|Proteomes:UP000009277};
RX   PubMed=22123768; DOI=10.1128/JB.06259-11;
RA   Oger P., Sokolova T.G., Kozhevnikova D.A., Chernyh N.A., Bartlett D.H.,
RA   Bonch-Osmolovskaya E.A., Lebedinsky A.V.;
RT   "Complete Genome Sequence of the Hyperthermophilic Archaeon Thermococcus
RT   sp. Strain AM4, Capable of Organotrophic Growth and Growth at the Expense
RT   of Hydrogenogenic or Sulfidogenic Oxidation of Carbon Monoxide.";
RL   J. Bacteriol. 193:7019-7020(2011).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; CP002952; EEB73409.1; -; Genomic_DNA.
DR   RefSeq; WP_014122829.1; NC_016051.1.
DR   AlphaFoldDB; B7R3K4; -.
DR   STRING; 246969.TAM4_1157; -.
DR   GeneID; 7420456; -.
DR   KEGG; tha:TAM4_1157; -.
DR   eggNOG; arCOG04138; Archaea.
DR   HOGENOM; CLU_025558_1_0_2; -.
DR   OrthoDB; 85892at2157; -.
DR   Proteomes; UP000009277; Chromosome.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   Gene3D; 1.20.1460.20; -; 1.
DR   Gene3D; 3.30.70.2170; -; 1.
DR   Gene3D; 3.30.70.2750; -; 1.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR   PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR   Pfam; PF01496; V_ATPase_I; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM        376..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        411..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        464..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        505..524
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        530..556
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        568..590
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        596..621
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   COILED          116..143
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          233..267
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   666 AA;  74955 MW;  46437C429F8754C1 CRC64;
     MFRPAEMLKV ELITLERYRD KLLTYLHEAG VVEIREVDVK IAQRDAPNEF YRKAASYAIT
     ISRMADFLRA HLPAKGGGIK EFIFPREPEK KEYHYRGIER LIKDTEKFLA EVEPLVKAVE
     GRISSINTEI ERIKADIEIL EMLSSFNIDV SYLRHSGTVT VLVGTVDRAK FPALMEELSS
     ALEGRVAVVH RDLKDTVVMA LAFLTKDYDK ANPVLAKHSF ERLEIPKGEG TPSELLKEYR
     RMLSKKLDEL EEARREASEI AEKYYRDVLF YLELVENERN KANALSMLAR TNMTFALTGW
     VPEEEAKKVE EGVREVTNGV VYVSFKKPEK EELEEIPIKL KNPSWARPFE MLTEMYGVPR
     YDEIDPTPII AFTYSFFFGF MLTDFMYGLI VGIVAALLVK GHRKFNDGTY KFAYTLLISS
     FFTMLMGILF GSYFGNAGDV VLQHLTGNPK AQFWRIADPL KQPMFVLMLA LAIGLAHLFT
     GYTIGFIVKW KNGDRKGALL EQLPWMLIIL AIVLFAATGS AVLAKPLFGI GIVLFAIGEI
     VANGGLAALM IISDFFGFVG TWLSYARLMA LALATGGIAM VINVLARMVW GIKISVVPLG
     IIVGLIIFIG GQLFSTAINA LGAFVHSLRL QYVEFFGTFY SGDGKPFEPF RARRVFSKLK
     LESGSE
//