ID B7R523_9EURY Unreviewed; 444 AA.
AC B7R523;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Beta-galactosidase trimerisation domain-containing protein {ECO:0000259|Pfam:PF08532};
GN ORFNames=TAM4_2051 {ECO:0000313|EMBL:EEB73194.1};
OS Thermococcus sp. AM4.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=246969 {ECO:0000313|EMBL:EEB73194.1, ECO:0000313|Proteomes:UP000009277};
RN [1] {ECO:0000313|EMBL:EEB73194.1, ECO:0000313|Proteomes:UP000009277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM4 {ECO:0000313|EMBL:EEB73194.1,
RC ECO:0000313|Proteomes:UP000009277};
RX PubMed=22123768; DOI=10.1128/JB.06259-11;
RA Oger P., Sokolova T.G., Kozhevnikova D.A., Chernyh N.A., Bartlett D.H.,
RA Bonch-Osmolovskaya E.A., Lebedinsky A.V.;
RT "Complete Genome Sequence of the Hyperthermophilic Archaeon Thermococcus
RT sp. Strain AM4, Capable of Organotrophic Growth and Growth at the Expense
RT of Hydrogenogenic or Sulfidogenic Oxidation of Carbon Monoxide.";
RL J. Bacteriol. 193:7019-7020(2011).
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DR EMBL; CP002952; EEB73194.1; -; Genomic_DNA.
DR RefSeq; WP_014121694.1; NC_016051.1.
DR AlphaFoldDB; B7R523; -.
DR STRING; 246969.TAM4_2051; -.
DR GeneID; 7419143; -.
DR KEGG; tha:TAM4_2051; -.
DR eggNOG; arCOG02611; Archaea.
DR HOGENOM; CLU_614854_0_0_2; -.
DR OrthoDB; 101158at2157; -.
DR Proteomes; UP000009277; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR013738; Beta_galactosidase_Trimer.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF08532; Glyco_hydro_42M; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 260..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 104..209
FT /note="Beta-galactosidase trimerisation"
FT /evidence="ECO:0000259|Pfam:PF08532"
SQ SEQUENCE 444 AA; 50069 MW; FDF0787EBB19A91D CRC64;
MTRLGSKLLV VFLFFALLFH LPPNYASPNE KARILVVCSD PEDVMFANTL GAEGNFTVDV
LYLGRDLPDD RSLLSNELYL IKYDEIWIPD LNAGLTEGGR LNREETSALA EYVRRGGVLV
LGLNTYTQSW SRTLERITGT RLMRIEKPEE ASDEWNLVFE GRVYPYNATY QVAVVTPYRA
QVLARYSNGL PAVTLSRYGR GVGVLMTFNP VKELVEYNPE IIDVYVHVAN IALSERSGKP
EIPAGEAVLL KLERVLLHPV FLGVLVFVLL EIMAYLGFLP FSVTVLFAVP LLPFSRFLLG
RAPYSAILEI VRMLRGVTLG NLADEIGRSP RRLKFPLALL FLKKQISVID LSPFGFKDVL
VVLRGLEGDG VAAWAIEVYP RMMEIIASNP GIGVIDLARQ VNMPPYDVLR LLRELSRYGV
VELRKIVVDY EVYPMRPLLR WFEV
//
