ID B7R910_9THEO Unreviewed; 444 AA.
AC B7R910;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Permease {ECO:0000313|EMBL:KKC30348.1};
GN ORFNames=CDSM653_00605 {ECO:0000313|EMBL:KKC30348.1};
OS Caldanaerobacter subterraneus subsp. pacificus DSM 12653.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Caldanaerobacter.
OX NCBI_TaxID=391606 {ECO:0000313|EMBL:KKC30348.1, ECO:0000313|Proteomes:UP000010146};
RN [1] {ECO:0000313|EMBL:KKC30348.1, ECO:0000313|Proteomes:UP000010146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12653 {ECO:0000313|EMBL:KKC30348.1,
RC ECO:0000313|Proteomes:UP000010146};
RA Gonzalez J., Sokolova T., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KKC30348.1, ECO:0000313|Proteomes:UP000010146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12653 {ECO:0000313|EMBL:KKC30348.1,
RC ECO:0000313|Proteomes:UP000010146};
RX PubMed=26446804; DOI=10.1186/s12864-015-1955-9;
RA Sant'Anna F.H., Lebedinsky A.V., Sokolova T.G., Robb F.T., Gonzalez J.M.;
RT "Analysis of three genomes within the thermophilic bacterial species
RT Caldanaerobacter subterraneus with a focus on carbon monoxide dehydrogenase
RT evolution and hydrolase diversity.";
RL BMC Genomics 16:757-757(2015).
RN [3] {ECO:0000313|Proteomes:UP000010146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12653 {ECO:0000313|Proteomes:UP000010146};
RA Sant'Anna F.H., Lebedinsky A., Sokolova T., Robb F.T., Gonzalez J.M.;
RT "Genome analysis of three genomes within the thermophilic hydrogenogenic
RT bacterial species Caldanaerobacter subterraneus.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC ECO:0000256|PIRNR:PIRNR005353}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKC30348.1}.
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DR EMBL; ABXP02000036; KKC30348.1; -; Genomic_DNA.
DR RefSeq; WP_009610782.1; NZ_ABXP02000036.1.
DR AlphaFoldDB; B7R910; -.
DR Proteomes; UP000010146; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR026033; Azg-like_bact_archaea.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PIRSF; PIRSF005353; PbuG; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 444 AA; 47045 MW; 4B97ABF6FB42125D CRC64;
MKDKTNLQNG LIERLFKLRE RNTDFKTEVL AGATTFITLA YIIFVNPQIL SEAGIPKEAA
IAATIWSSAI ATTLMALLAN YPIAVAPGMG LNAFFTYTVV KQFGLHWTVA LGAVFFSGVV
FLVLTVTKIR SWIIEAVPPS LRSAIPVGIG LFIAFIGLIN AGIVVKSDAT LVAFGHILKP
ETLLSIFGLI LAAVLISRGV RGALIISILT TTAVAMIFGV SPLPKGIGDV ISLHIPSLAP
TFGKLDIAGA FHYGLLNIIF TFTIVELFDN MGTLMGLLKK AGLLGEKGEP KALGRAFISD
SVGTMISPVL GTCTVTSYIE SAAGIAEGGK TGLTGITVAV FFLLALFIAP LVGLVPAFAT
APALIIVGAL MMTEIVHINF EDFTEAFPAF ITVIGMPLTY SIATGLGLGF ISYTLVKLLS
GRAKKIHWMM YVIAAAFTIN FVLR
//
