ID B7S1S3_9GAMM Unreviewed; 787 AA.
AC B7S1S3;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Cyclic diguanylate phosphodiesterase domain protein {ECO:0000313|EMBL:EEB77379.1};
GN ORFNames=GPB2148_1180 {ECO:0000313|EMBL:EEB77379.1};
OS marine gamma proteobacterium HTCC2148.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=247634 {ECO:0000313|EMBL:EEB77379.1, ECO:0000313|Proteomes:UP000002793};
RN [1] {ECO:0000313|Proteomes:UP000002793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2148 {ECO:0000313|Proteomes:UP000002793};
RX PubMed=20472793; DOI=10.1128/jb.00511-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT OM60/NOR5 clade of the Gammaproteobacteria.";
RL J. Bacteriol. 192:3842-3843(2010).
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DR EMBL; DS999235; EEB77379.1; -; Genomic_DNA.
DR AlphaFoldDB; B7S1S3; -.
DR STRING; 247634.GPB2148_1180; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_46_6; -.
DR Proteomes; UP000002793; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002793};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 240..292
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 367..512
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 521..774
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 787 AA; 85515 MW; DA542745445AB92B CRC64;
MRQASRITGG AGSLSISARF SLLIALAIVL MGIVSGLTTA SRDYSTQLSV VTGRVESELL
SHPDLQFAIY GADTQRLKTR LDEFLREDSS ASAQAYNGQG KMLVSAQRPG ATAFTPAAFN
LIRRSLLPGD PGLLSFDSST GTPQETGFSS ALFDPDAPIY QTLPVFTEVN TGKTGLSATD
FAIAMTMKPS SSSQRVIGYL QVLWDPSVLR SKAIAAGTRV LMINIVFALM CGAIAWAFTY
RVTRPLRELA NIADSVASGQ IKEPIKVQGS GEIQEIARLF NSVIEGLSDS KKVHEVDKRL
LSLKVEERSS QLSERNVELN KVVEEANEAK NRAHHLANYD NLTSLPNRRL LTEQLDLLLK
LNQRNGHTLA LLFIDLDDFK RVNDSLGIGA GDQLLVEVAR RLSHAVRDSD SVGRYASSNT
EIDVARLGGD EFTVILNQLD TAGSAQLVAQ RLVQKLTAPL AIEGRDLVLH PSLGIAIAPN
DGKDVESLLK AASIAKFHAK QTDGARIGIY QSNMAQEGED RLRLESDLRK AVKSNALSLH
YQPQIDTHSG SVLGAEALLR WEHPELGSIP PEKFITLAED IGLMGQLGDW VLVQACQQLR
SFEDEGIKLA KVAINVSAEQ FTPTFIQRVG VVIDETGIDP RQLELGLTEA VMSSNDPETI
ASLALLKASG VYLSVDDFGT GYSPINYLAQ YPLDEIKIDR SFLIDAEKSD NGANLVIAII
AMAKSMELRV LASGVETESQ FHFLTRNGAS LIQGYLFSKP VPAEELKPML APWHFVDRVQ
KLADSAP
//
