ID B7SES0_9NEOP Unreviewed; 396 AA.
AC B7SES0;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Elongation factor 1-alpha {ECO:0000256|ARBA:ARBA00013870};
DE Flags: Fragment;
GN Name=EF-1alpha {ECO:0000313|EMBL:ACA53111.1};
OS Actinote pyrrha pyrrha.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Heliconiinae; Acraeini; Actinote.
OX NCBI_TaxID=501989 {ECO:0000313|EMBL:ACA53111.1};
RN [1] {ECO:0000313|EMBL:ACA53111.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18191590; DOI=10.1016/j.ympev.2007.11.024;
RA Silva-Brandao K.L., Wahlberg N., Francini R.B., Azeredo-Espin A.M.,
RA Brown K.S.Jr., Paluch M., Lees D.C., Freitas A.V.;
RT "Phylogenetic relationships of butterflies of the tribe Acraeini
RT (Lepidoptera, Nymphalidae, Heliconiinae) and the evolution of host plant
RT use.";
RL Mol. Phylogenet. Evol. 46:515-531(2008).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; EU275689; ACA53111.1; -; Genomic_DNA.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:ACA53111.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000313|EMBL:ACA53111.1}.
FT DOMAIN 1..228
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 366..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACA53111.1"
FT NON_TER 396
FT /evidence="ECO:0000313|EMBL:ACA53111.1"
SQ SEQUENCE 396 AA; 43212 MW; 5CEA9D34F8928D0B CRC64;
HVDSGKSTTT GHLIYKCGGI DKRTIEKFEK EAQEMGKGSF KYAWVLDKLK AERERGXTID
IALWKFETAK YYVTIIDAPG HRDFIKNMXT GTSQADCAVL IVAAGTGEFE AGISKNGQTR
EHALLAFTLG VXQLIVGVNK MDSTEPPFSE PRFEEIKKEV SSYIKKIGYN PAAVAFVPIS
GWHGDNMLEP STKMPWFKGW QVERKEGKAE GKCLIEALDA ILPPARPTDK ALRLPLQDVY
KIGGIGTVPV GRVETGVLKP GTIVVFAPAN ITTEVKSVEM HHEALQEAVP GDNVGFNVKN
VSVKELRRGY VAGDSKNNPP RGAADFTAQV IVLNHPGQIS NGYTPVLDCH TAHIACKFAE
IKEKVDRRSG KSTEENPKSI KSGDAAIVNL QPSKPL
//
