ID B7SLA7_9HYPO Unreviewed; 265 AA.
AC B7SLA7;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
DE Flags: Fragment;
GN Name=ech42 {ECO:0000313|EMBL:ACD46761.1};
OS Trichoderma aethiopicum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=1195187 {ECO:0000313|EMBL:ACD46761.1};
RN [1] {ECO:0000313|EMBL:ACD46761.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PPRC J11 {ECO:0000313|EMBL:ACD46761.1};
RX PubMed=18957598; DOI=10.1099/mic.0.2008/021196-0;
RA Druzhinina I.S., Komon-Zelazowska M., Kredics L., Hatvani L., Antal Z.,
RA Belayneh T., Kubicek C.P.;
RT "Alternative reproductive strategies of Hypocrea orientalis and genetically
RT close but clonal Trichoderma longibrachiatum, both capable of causing
RT invasive mycoses of humans.";
RL Microbiology 154:3447-3459(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class V subfamily. {ECO:0000256|ARBA:ARBA00008682}.
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DR EMBL; EU401533; ACD46761.1; -; Genomic_DNA.
DR AlphaFoldDB; B7SLA7; -.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..256
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACD46761.1"
FT NON_TER 265
FT /evidence="ECO:0000313|EMBL:ACD46761.1"
SQ SEQUENCE 265 AA; 28515 MW; EA1875EBCA65312B CRC64;
PRKRFASTAI TFMKDWGFDG IDIDWEYPAD STQASNMILL LKEVRSQLDA YAAQHAPGYH
FLLSIAAPAG EVNYSVLRLA DLGQVLDYVN LMAYDYAGSW SNASGHDANL YANPQNPNAT
PFNTDDAVKA YIKGGVPANK IVLGMPIYGR SFESTSGIGQ PFNGIGSGSW ENGVWDYKAL
PKAGATVQYD DVAKASYSYD PSTKELISFD TPDVINTKVA YLKSLGLGGS MFWEASADKK
GADSLIGTSH KALGALDSTQ NLLSP
//
