ID   B7XJ80_ENTBH            Unreviewed;      1669 AA.
AC   B7XJ80;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Dynein heavy chain {ECO:0000313|EMBL:EED44023.1};
GN   ORFNames=EBI_22336 {ECO:0000313|EMBL:EED44023.1};
OS   Enterocytozoon bieneusi (strain H348) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Enterocytozoonidae;
OC   Enterocytozoon.
OX   NCBI_TaxID=481877 {ECO:0000313|EMBL:EED44023.1, ECO:0000313|Proteomes:UP000001742};
RN   [1] {ECO:0000313|EMBL:EED44023.1, ECO:0000313|Proteomes:UP000001742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H348 {ECO:0000313|EMBL:EED44023.1,
RC   ECO:0000313|Proteomes:UP000001742};
RX   PubMed=18060071; DOI=10.1371/journal.pone.0001277;
RA   Corradi N., Akiyoshi D.E., Morrison H.G., Feng X., Weiss L.M., Tzipori S.,
RA   Keeling P.J.;
RT   "Patterns of genome evolution among the microsporidian parasites
RT   Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon
RT   bieneusi.";
RL   PLoS ONE 2:E1277-E1277(2007).
RN   [2] {ECO:0000313|EMBL:EED44023.1, ECO:0000313|Proteomes:UP000001742}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H348 {ECO:0000313|EMBL:EED44023.1,
RC   ECO:0000313|Proteomes:UP000001742};
RX   PubMed=19132089; DOI=10.1371/journal.ppat.1000261;
RA   Akiyoshi D.E., Morrison H.G., Lei S., Feng X., Zhang Q., Corradi N.,
RA   Mayanja H., Tumwine J.K., Keeling P.J., Weiss L.M., Tzipori S.;
RT   "Genomic survey of the non-cultivatable opportunistic human pathogen,
RT   Enterocytozoon bieneusi.";
RL   PLoS Pathog. 5:E1000261-E1000261(2009).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EED44023.1}.
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DR   EMBL; ABGB01000025; EED44023.1; -; Genomic_DNA.
DR   RefSeq; XP_002650058.1; XM_002650012.1.
DR   STRING; 481877.B7XJ80; -.
DR   VEuPathDB; MicrosporidiaDB:EBI_22336; -.
DR   HOGENOM; CLU_241862_0_0_1; -.
DR   InParanoid; B7XJ80; -.
DR   OrthoDB; 1221059at2759; -.
DR   Proteomes; UP000001742; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR040848; AAA_lid_7.
DR   InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR   PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR   Pfam; PF07728; AAA_5; 4.
DR   Pfam; PF17867; AAA_lid_7; 1.
DR   SMART; SM00382; AAA; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 5.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001742}.
FT   DOMAIN          286..556
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          898..1040
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          1147..1289
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
SQ   SEQUENCE   1669 AA;  194936 MW;  3D87600A7FAC59D4 CRC64;
     MHHVLFHSCN EDSIIAEIKQ SVQINYPVVL YGNKGKTFLL THLYPDIIIV DSREIYDVRM
     LTGFYTFKDH DLIFTEGLLT KALRIGQKLC FKRIDENIAL QQYLIPIVSN EEVYTNQGIK
     IQIHNEFRIF FTSSKKFNYR NVNFIGEIGF YKNDIFSKIP DNIKDVVIEW NGIFNENTNC
     KYLSGEECDN VCYKEINCYC NEVFICNEHF LQYTKFINNT FHLKNIKEDR LQLYQSIVNQ
     FLKHDSKIVL ERLYLEPSTI DINIINMAIT NPIKMAFSAI QFNIQNKIPT LLVGSTGVGK
     TALIQEFAKL HNTPIQIINC SSEFDGFDLL GGFKLFNFEK QLQMVINQFK TLFPDINFQL
     SIDDLLLHFN DILIRYKAKI DNKIIIKLIN EVKLLSKIYK NKLCFEYKEG LLLDAMKHGK
     WILLDEINLA SHETLNLIES ILSKNHFLIQ ETNEYFTIHQ NFMLFGCMNP FGDFGKKKFD
     SMQFNRIEFY DFSCNLHDIR QVCNFILKEN NDLTEKLCIF FYQFRLRVVQ HVFVNMLEPI
     ITGRTFCRLL YLLKNNLTVE QIYKACCLLL FTQLNINSRA QALSLFQELF KINSFVFNLD
     TLPLNNYILT ESMKIILSDI LLAIEYRFPI LLQGATSVGK TSIIFSIANY KQIKTIRINN
     HESTDITDYI GQYVTNDGLF SFKYGPLIKA IKNGWWIILD ELNLAQSDVL EALNRLLDDN
     NEIYITETNE LIKPHPQFRL FATQNINYSG RNGLAKSFRN RFVEINFPEK NEYEINQILK
     ELYNFPKSFI NLIVETYTKL NTINEIQLSG KLTLRDILKW CNRKPSTFNE LYFYGIQLFV
     EKIRSNRYKV SNMLYSIFKS KITLEAINND NYLINHDKFI LTDSYKSLIQ SIKTALNFYE
     PVLLIGETGI GKTLVCEVVA SLLNKKIVIF NFSENTEISD LLGHYEFING NIIWKEGILI
     ESLKTNCIFV MDEINLCPSG VLERFNSLFE TEKTIYITEL NETFQFSNSQ IIATMNPAGD
     FGKKELTPAF RNRFTEIYFT ITPEEKLNIF KSKTHGLILD NKIYELVSQI SLRKSDLVAN
     LIQLLETNNK EIEIIKNGNL YDEICDFLNI NSKCNYKYIF KSMKLESTKF YVHFENKINK
     IARAFLFSHP ILLCGPPGCG KTSLINSIAS IVNKKLLRIN LSENTEITDL LGNLIPQGNN
     IQFYESEFVN YLIEGNWIIL DEINLCSQTV LEGLNSILDY RKSIMVNNKQ VIVNKNTRIF
     GTMNPCTIKG RKQLPRSFLD RFIQINISDY TAIEIKSILS NITTNYSYNE YLSLRGNLKL
     NIMNQIKTNV DINKYHLLMH DKYTEDYEYD NIIFRIKDIF IYAPNINTDF VLIPSQLPQI
     YEILACSLNK IPIILKGNIG RKPVINFVGK LLQLPVNHIY YSKSTDISDL IGGYQKSKSE
     LFIWKNSKLI DLLMSEGIIV LHNADQIDKS IFDRLNSLFE FERKLLIYEK VIKEEIKVPS
     KTIFILFSDD ETIFSESILD RCHVVNLSDK YNHIDLLKIN SKTINPNKIE VHITDISLLN
     SIENELQNIN IEKFTRYNNY KYYMRNLLQT TAIEAYCNIS CEQINNVELD KEIINYYEEC
     LQFKKTNEWK LLNIYFTKLD SRLWDDKFIT STLVKHKFIE SLRNKTIDG
//